Anti-SYN2 抗体 (ab13258)
Key features and details
- Rabbit polyclonal to SYN2
- Suitable for: IP, ICC/IF, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-SYN2 antibody
SYN2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SYN2 -
由来種
Rabbit -
アプリケーション
適用あり: IP, ICC/IF, WBmore details -
種交差性
交差種: Mouse, Rat
交差が予測される動物種: Human
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免疫原
Synthetic peptide corresponding to Rat SYN2 aa 50-150 conjugated to keyhole limpet haemocyanin.
Database link: Q63537 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab13258の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| ICC/IF |
Use at an assay dependent concentration. PubMed: 19714568
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. PubMed: 19714568 |
|
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. -
組織特異性
Central and peripheral nervous systems. -
配列類似性
Belongs to the synapsin family. -
ドメイン
The A region binds phospholipids with a preference for negatively charged species. -
翻訳後修飾
Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons. -
細胞内局在
Cell junction, synapse. - Information by UniProt
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参照データベース
- Entrez Gene: 6854 Human
- Entrez Gene: 20965 Mouse
- Entrez Gene: 29179 Rat
- Omim: 600755 Human
- SwissProt: Q92777 Human
- SwissProt: Q64332 Mouse
- SwissProt: Q63537 Rat
- Unigene: 445503 Human
see all -
別名
- SYN 2 antibody
- SYN II antibody
- SYN IIa antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab13258 は 11 報の論文で使用されています。
- Schwark R et al. Synapsin II Directly Suppresses Epileptic Seizures In Vivo. Brain Sci 12:N/A (2022). PubMed: 35326282
- Dreumont N et al. Glucocorticoid Receptor Activation Restores Learning Memory by Modulating Hippocampal Plasticity in a Mouse Model of Brain Vitamin B12 Deficiency. Mol Neurobiol 58:1024-1035 (2021). PubMed: 33078371
- Liu SB et al. Cyclic AMP-dependent positive feedback signaling pathways in the cortex contributes to visceral pain. J Neurochem 153:252-263 (2020). PubMed: 31665810
- Jadhav VS et al. Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice. Mol Neurodegener 15:62 (2020). PubMed: 33115519
- Plumel M et al. Circadian Analysis of the Mouse Cerebellum Proteome. Int J Mol Sci 20:N/A (2019). PubMed: 30991638