Anti-Superoxide Dismutase 3/EC-SOD 抗体 (ab83108)
Key features and details
- Rabbit polyclonal to Superoxide Dismutase 3/EC-SOD
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Superoxide Dismutase 3/EC-SOD antibody
Superoxide Dismutase 3/EC-SOD 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Superoxide Dismutase 3/EC-SOD -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human
交差が予測される動物種: Rabbit
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免疫原
Synthetic peptide corresponding to Superoxide Dismutase 3/EC-SOD.
Database link: P08294 -
ポジティブ･コントロール
- Rat and mouse Lung Tissue Extract; Human Superoxide Dismutase 3/EC-SOD Protein.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab83108の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 26 kDa).
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| 特記事項 |
|---|
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WB
1/1000. Detects a band of approximately 35 kDa (predicted molecular weight: 26 kDa). |
ターゲット情報
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機能
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. -
組織特異性
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. -
配列類似性
Belongs to the Cu-Zn superoxide dismutase family. -
細胞内局在
Secreted > extracellular space. 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. - Information by UniProt
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参照データベース
- Entrez Gene: 6649 Human
- Entrez Gene: 20657 Mouse
- Entrez Gene: 25352 Rat
- Omim: 185490 Human
- SwissProt: P08294 Human
- SwissProt: O09164 Mouse
- SwissProt: P41975 Rabbit
- SwissProt: Q08420 Rat
see all -
別名
- EC SOD antibody
- EC-SOD antibody
- Extracellular superoxide dismutase [Cu Zn] antibody
see all
画像
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Western blot - Anti-Superoxide Dismutase 3/EC-SOD antibody (ab83108)All lanes : Anti-Superoxide Dismutase 3/EC-SOD antibody (ab83108) at 1/1000 dilution
Lane 1 : Rat lung tissue extract
Lane 2 : Mouse lung tissue extract
Lane 3 : Human Superoxide Dismutase 3/EC-SOD protein
Developed using the ECL technique.
Predicted band size: 26 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
Additional bands at: 40 kDa (possible glycosylated form), 60 kDa (possible dimer)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab83108 は 11 報の論文で使用されています。
- Tsao CW et al. Effects of Iron Supplementation on Testicular Function and Spermatogenesis of Iron-Deficient Rats. Nutrients 14:N/A (2022). PubMed: 35631204
- Cen Y et al. APPL1 ameliorates myocardial ischemia-reperfusion injury by regulating the AMPK signaling pathway. Exp Ther Med 23:157 (2022). PubMed: 35069838
- Lavier J et al. High-intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice. Acta Physiol (Oxf) 233:e13700 (2021). PubMed: 34089562
- Pariano M et al. Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity. Int J Mol Sci 22:N/A (2021). PubMed: 34207085
- Ikelle L et al. Modulation of SOD3 Levels Is Detrimental to Retinal Homeostasis. Antioxidants (Basel) 10:N/A (2021). PubMed: 34679728