Anti-Sulfatase 1/SULF1 抗体 (ab168616)
Key features and details
- Mouse polyclonal to Sulfatase 1/SULF1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Sulfatase 1/SULF1 antibody
Sulfatase 1/SULF1 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to Sulfatase 1/SULF1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant full length protein within Human Sulfatase 1/SULF1 aa 1-900. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: NP_055985 -
ポジティブ･コントロール
- Sulfatase 1/SULF1 transfected 293T cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.4
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab168616の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa. |
ターゲット情報
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機能
Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation. -
組織特異性
Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines. -
配列類似性
Belongs to the sulfatase family. -
翻訳後修飾
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. -
細胞内局在
Endoplasmic reticulum. Golgi apparatus > Golgi stack. Cell surface. Also localized on the cell surface. - Information by UniProt
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参照データベース
- Entrez Gene: 23213 Human
- Entrez Gene: 240725 Mouse
- Entrez Gene: 171396 Rat
- Omim: 610012 Human
- SwissProt: Q8IWU6 Human
- SwissProt: Q8K007 Mouse
- SwissProt: Q8VI60 Rat
- Unigene: 409602 Human
see all -
別名
- DSulf antibody
- Extracellular sulfatase Sulf 1 antibody
- Extracellular sulfatase Sulf-1 antibody
see all
画像
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Western blot - Anti-Sulfatase 1/SULF1 antibody (ab168616)All lanes : Anti-Sulfatase 1/SULF1 antibody (ab168616) at 1 µg/ml
Lane 1 : Sulfatase 1/SULF1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 101 kDa
データシートおよび資料
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Datasheet download
参考文献 (0)
ab168616 は論文での使用が確認できていません。
