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AB69678

Anti-STK31 抗体

Anti-STK31 antibody

4

(1 Review)

|

(2 Publications)

Mouse Polyclonal STK31 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human STK31.

別名を表示する

SGK396, STK31, Serine/threonine-protein kinase 31, Serine/threonine-protein kinase NYD-SPK, Sugen kinase 396, SgK396

Key facts

宿主種

Mouse

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

Yes

交差種

Human

アプリケーション

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human STK31.

Q9BXU1

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代替製品

Primary Antibodies

AB155172

Anti-STK31 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STK31 antibody (AB155172)

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組合せ製品

Primary Antibodies

AB314900

Anti-Zinc finger antiviral protein antibody [EPR28538-63] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Zinc finger antiviral protein antibody [EPR28538-63] - BSA and Azide free (AB314900)

  • 0
  • 0
Primary Antibodies

AB74504

Anti-ZDHHC9 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZDHHC9 antibody (AB74504)

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  • 0
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 16
Primary Antibodies

AB8227

Anti-beta Actin antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Western blot - Anti-beta Actin antibody - Loading Control (AB8227)

  • 5
  • 104
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

STK31 also known as Serine/Threonine Kinase 31 or TDRD8 is a protein kinase involved in phosphorylation processes. This protein has a molecular weight of approximately 67 kDa. It is mostly expressed in testicular tissue where it contributes to germ cell development. The expression of STK31 might vary depending on the developmental stage and cellular environment suggesting a role in reproductive biology.
Biological function summary

The activity of STK31 impacts cellular processes critical for germ cell maturation and division. STK31 interacts within complex networks of proteins and possibly forms part of a larger protein complex involved in orchestrating cell cycle progression. Its enzymatic role aids in regulating checkpoints during cell division ensuring proper cellular replication and integrity within reproductive tissues.

Pathways

The role of STK31 is significant in the regulation of the cell cycle and PI3K/AKT signaling pathways. This kinase participates in signaling cascades that control cell proliferation and survival aligning with its primary function in germ cells. STK31's activity relates to other proteins in these pathways such as CDK and AKT which mediate various aspects of cellular growth and replication helping maintain balance and function in cellular contexts.

STK31 has connections to germ cell tumors and testicular cancer. Aberrant expression or mutations of STK31 are associated with testicular germ cell tumors indicating its critical role in normal and pathological conditions. It shares a link with proteins like OCT4 and NANOG which are known for roles in stem cell pluripotency and are found deregulated in certain cancers implicating STK31 in oncogenic processes within reproductive tissues.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

See full target information STK31
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Proceedings of the National Academy of Sciences of the United States of America 117:19408-19414 PubMed32719138

2020

CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression.

Applications

Unspecified application

Species

Unspecified reactive species

Michael P Crawford,Sushmita Sinha,Pranav S Renavikar,Nicholas Borcherding,Nitin J Karandikar

Oncology reports 43:395-404 PubMed31894338

2020

STK31 regulates the proliferation and cell cycle of lung cancer cells via the Wnt/β‑catenin pathway and feedback regulation by c‑myc.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Xiong,Shigang Xing,Zheng Dong,Lei Niu,Qinghua Xu,Pingyi Liu,Peixia Yang
View all publications
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Abcam product promise

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