Anti-STEAP4 抗体 (ab113230)
Key features and details
- Rabbit polyclonal to STEAP4
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-STEAP4 antibody
STEAP4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to STEAP4 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide conjugated to KLH from Human STEAP4.
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ポジティブ･コントロール
- Human Liver and Skin tissues; HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS (without Mg2+, Ca2+) -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113230の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml.
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| ICC/IF |
1/100 - 1/500.
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| 特記事項 |
|---|
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IHC-P
Use a concentration of 10 µg/ml. |
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ICC/IF
1/100 - 1/500. |
ターゲット情報
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機能
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. -
組織特異性
Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. -
配列類似性
Belongs to the STEAP family.
Contains 1 ferric oxidoreductase domain. -
細胞内局在
Cell membrane. Golgi apparatus membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 79689 Human
- Omim: 611098 Human
- SwissProt: Q687X5 Human
- Unigene: 521008 Human
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別名
- alpha-induced protein 9 antibody
- Metalloreductase STEAP4 antibody
- six transmembrane prostate protein 2 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STEAP4 antibody (ab113230)ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STEAP4 antibody (ab113230)ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Skin tissue by Immunohistochemistry. -
Immunocytochemistry/ Immunofluorescence - Anti-STEAP4 antibody (ab113230)ab113230 at 1/100 dilution staining STEAP4 in HeLa cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab113230 は論文での使用が確認できていません。