Anti-SPAK 抗体 (ab79045)
Key features and details
- Rabbit polyclonal to SPAK
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-SPAK antibody
SPAK 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SPAK -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to Human SPAK (internal sequence).
Database link: NP_037365 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Affinity chromatography purified via peptide column -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab79045の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 60 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 60 kDa. |
ターゲット情報
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機能
May act as a mediator of stress-activated signals. -
組織特異性
Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis. -
配列類似性
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain. -
ドメイン
PAPA box (proline-alanine repeats) may target the kinase to a specific subcellular location by facilitating interaction with intracellular proteins such as actin or actin-like proteins. -
細胞内局在
Cytoplasm. Nucleus. Nucleus when caspase-cleaved. - Information by UniProt
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参照データベース
- Entrez Gene: 54348 Rat
- SwissProt: O88506 Rat
- Unigene: 34414 Rat
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別名
- DCHT antibody
- DKFZp686K05124 antibody
- OTTHUMP00000165175 antibody
see all
画像
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Western blot - Anti-SPAK antibody (ab79045)Lane 1 : Anti-SPAK antibody (ab79045) at 1 µg/ml
Lane 2 : Anti-SPAK antibody (ab79045) at 2 µg/ml
All lanes : rat brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 60 kDa
Observed band size: 60 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab79045 は 2 報の論文で使用されています。
- Sekii Y et al. Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway. Commun Biol 5:175 (2022). PubMed: 35228649
- Yang HJ et al. Melatonin modulates nitric oxide-regulated WNK-SPAK/OSR1-NKCC1 signaling in dorsal raphe nucleus of rats. Korean J Physiol Pharmacol 25:449-457 (2021). PubMed: 34448462