AB27655

Anti-SOX8 抗体

Name: Anti-SOX8 抗体 (ab27655) | Abcam
Brand: Abcam Limited
SKU: AB27655
Price: 74000 JPY
Availability: InStock
Rating: 4 (6 reviews)

Anti-SOX8 antibody

(6 Reviews)

(20 Publications)

Rabbit Polyclonal SOX8 antibody. Suitable for WB, IHC-P and reacts with Mouse, Chicken samples. Cited in 20 publications. Immunogen corresponding to Synthetic Peptide within Chicken SOX8 aa 400 to C-terminus.

別名を表示する

Transcription factor SOX-8, SOX8

2 Images

Unknown

Western blot - Anti-SOX8 antibody (AB27655)

SOX10 contains a number of potential phosphorylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted.

All lanes:

Western blot - Anti-SOX8 antibody (ab27655) at 1/500 dilution

Lane 1:

Brain (Mouse) Tissue Lysate at 10 µg

Lane 2:

Heart (Mouse) Tissue Lysate at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 47 kDa

Observed band size: 100 kDa,56 kDa,74 kDa

true

Exposure time: 8min

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX8 antibody (AB27655)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX8 antibody (AB27655)

Sections through the trunk of E4 chick embryos fixed in 4 % paraformaldehyde and stained with anti-SOX10 (ab27655) diluted 1/5000. Secondary antibody was FITC-conjugated donkey anti-rabbit. ab27655 stains the embryonic neural crest cells which can be seen migrating into the dorsal root ganglion.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Mouse, Chicken

アプリケーション

IHC-P, WB

applications

免疫原

Synthetic Peptide within Chicken SOX8 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P57074

特異性

Antibody was raised using a synthetic peptide corresponding to Sox8. However, this antibody demonstrates cross reactivity against Sox10. Does not cross react with SOX9

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chicken": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製度

Whole antiserum

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Transcription factor that may play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

See full target information SOX8

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文献 (20)

Recent publications for all applications. Explore the full list and refine your search

PLoS genetics 21:e1011693 PubMed40354322

2025

Molecular insights into region-specific sexual dichromatism: Comparative transcriptome analysis of red cheek pigmentation in zebra finches.

Applications

Unspecified application

Species

Unspecified reactive species

Gee-Way Lin,Chih-Kuan Chen,Ting-Xin Jiang,Ya-Chen Liang,Pin-Chi Tang,Ping Wu,Randall B Widelitz,Chih-Feng Chen,Cheng-Ming Chuong

Cell reports 41:111842 PubMed36543123

2022

SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wang,Sheng Zhang,Zhaohui Lan,Vui Doan,Bokyung Kim,Sihan Liu,Meina Zhu,Vanessa L Hull,Sami Rihani,Chun-Li Zhang,John A Gray,Fuzheng Guo

PLoS genetics 18:e1009765 PubMed35839257

2022

The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival.

Applications

Unspecified application

Species

Unspecified reactive species

Toshihiro Inubushi,Yuichiro Nakanishi,Makoto Abe,Yoshifumi Takahata,Riko Nishimura,Hiroshi Kurosaka,Fumitoshi Irie,Takashi Yamashiro,Yu Yamaguchi

Genesis (New York, N.Y. : 2000) 60:e23464 PubMed34897971

2021

The actin-cytoskeleton associating protein BASP1 regulates neural progenitor localization in the neural tube.

Applications

Unspecified application

Species

Unspecified reactive species

Kaitlin Mac Donald,Angelo Iulianella

Cell reports 37:109695 PubMed34610310

2021

PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wang,Yanhong Zhang,Sheng Zhang,Bokyung Kim,Vanessa L Hull,Jie Xu,Preeti Prabhu,Maria Gregory,Veronica Martinez-Cerdeno,Xinhua Zhan,Wenbin Deng,Fuzheng Guo

The Journal of neuroscience : the official journal of the Society for Neuroscience : PubMed33452226

2021

The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Sheng Zhang,Yan Wang,Xiaoqing Zhu,Lanying Song,Xinhua Zhan,Edric Ma,Jennifer McDonough,Hui Fu,Franca Cambi,Judith Grinspan,Fuzheng Guo

The Journal of neuroscience : the official journal of the Society for Neuroscience 41:251-268 PubMed33208471

2020

HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Sheng Zhang,Yan Wang,Jie Xu,Bokyung Kim,Wenbin Deng,Fuzheng Guo

Advanced biology 5:e2000134 PubMed32924336

2020

Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia.

Applications

Unspecified application

Species

Unspecified reactive species

Taida Huang,Yan Zhang,Zitian Wang,Yunxin Zeng,Nan Wang,Huaxun Fan,Zhangsen Huang,Yixun Su,Xiaomin Huang,Hui Chen,Kai Zhang,Chenju Yi

Glia 68:1148-1164 PubMed31851405

2019

Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination.

Applications

Unspecified application

Species

Unspecified reactive species

Evelien Fredrickx,Elisa Colombo,Paolo Canevazzi,Rosa La Marca,Marta Pellegatta,Giorgia Dina,Paola Podini,Klaus A Nave,Angelo Quattrini,Carla Taveggia

The Journal of comparative neurology 527:1654-1674 PubMed30552685

2018

Cortical interlaminar astrocytes across the therian mammal radiation.

Applications

Unspecified application

Species

Unspecified reactive species

Carmen Falcone,Marisol Wolf-Ochoa,Sarwat Amina,Tiffany Hong,Gelareh Vakilzadeh,William D Hopkins,Patrick R Hof,Chet C Sherwood,Paul R Manger,Stephen C Noctor,Verónica Martínez-Cerdeño

View all publications

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代替製品

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Primary Antibodies

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Primary Antibodies

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Primary Antibodies

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Primary Antibodies

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BOND RX™ Validated|20ul selling size|Recombinant|Advanced Validation|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX10 antibody [EPR4007-104] (AB180862)

組合せ製品

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

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Primary Antibodies

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Anti-SOX5 antibody

BOND RX™ Validated

Immunohistochemistry paraffin embedded sections - Anti-SOX5 antibody (AB94396)

Primary Antibodies

AB155279

Anti-SOX10 antibody [EPR4007]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Frozen sections) - Anti-SOX10 antibody [EPR4007] (AB155279)

Primary Antibodies

AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker

Immunohistochemistry (Frozen sections) - Anti-NeuN antibody [EPR12763] - Neuronal Marker (AB177487)

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