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Anti-SOX11 抗体 [CL0142] (ab154138)

Submit a review Submit a question References (2)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
  • Immunocytochemistry/ Immunofluorescence - Anti-SOX11 antibody [CL0142] (ab154138)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)

Key features and details

  • Mouse monoclonal [CL0142] to SOX11
  • Suitable for: ICC/IF, IHC-P
  • Reacts with: Mouse, Human
  • Isotype: IgG2a

製品の概要

  • 製品名

    Anti-SOX11 antibody [CL0142]
    SOX11 一次抗体 製品一覧

  • 製品の詳細

    Mouse monoclonal [CL0142] to SOX11

  • 由来種

    Mouse

  • アプリケーション

    適用あり: ICC/IF, IHC-Pmore details

  • 種交差性

    交差種: Mouse, Human
    交差が予測される動物種: Pig

  • 免疫原

    Recombinant fragment corresponding to amino acids 56-166 of Human SOX11.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • ポジティブ･コントロール

    • IHC-P: Human mantle cell lymphoma, mouse retina, and mouse brain tissues. ICC/IF: RH-30 cells.

  • 特記事項

    The antibody solution should be gently mixed before use.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab154138の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
ICC/IF
Use a concentration of 2 - 10 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
特記事項
ICC/IF
Use a concentration of 2 - 10 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)

    Immunohistochemical anaysis of human mantle cell lymphoma labeling SOX11 with ab154138 at 1/200 dilution.

    Shows moderate to strong nuclear positivity in tumor cells.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)

    Immunohistochemical anaysis of human chronic lymphoid leukemia tissue showing no labeling of SOX11 with ab154138 at 1/200 dilution (negative control).

    Shows no nuclear positivity in tumor cells as expected.

  • Immunocytochemistry/ Immunofluorescence - Anti-SOX11 antibody [CL0142] (ab154138)
    Immunocytochemistry/ Immunofluorescence - Anti-SOX11 antibody [CL0142] (ab154138)

    Immunocytochemistry/Immunofluorescence analysis of RH-30 cells labelling SOX11 with ab154138 at 2µg/ml.

    Shows specific staining in the nucleus and cytosol in green. Microtubule are visualized in red.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)

    Immunohistochemical anaysis of mouse embryo e14 retina labeling SOX11 with ab154138 at 1/200 dilution.

    Shows moderate nuclear positivity in developing retina.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SOX11 antibody [CL0142] (ab154138)

    Immunohistochemical anaysis of mouse embryo e14 labeling SOX11 with ab154138 at 1/200 dilution.

    Shows strong nuclear positivity in the developing forebrain.

参考文献 (2)

ab154138 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab154138 は 2 報の論文で使用されています。

  • Hussein D  et al. A paediatric dysembryoplastic neuroepithelial tumour (DNET) with deregulated stem cell markers: a case report. Transl Pediatr 11:1040-1049 (2022). PubMed: 35800288
  • Chang L  et al. miR-145 targets theSOX113'UTR to suppress endometrial cancer growth. Am J Cancer Res 7:2305-2317 (2017). PubMed: 29218252

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