Anti-Slit3 抗体 (ab11018)
Key features and details
- Rabbit polyclonal to Slit3
- Suitable for: WB
- Reacts with: Cow
- Isotype: IgG
製品の概要
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製品名
Anti-Slit3 antibody
Slit3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Slit3 -
由来種
Rabbit -
特異性
A BLAST analysis was used to suggest reactivity with this protein from human, rat, dog, bovine and mouse based on 100% homology for the immunogen sequence. Expect cross reactivity with SLIT-3 from chimpanzee and chicken sources, as only a single amino acid residue change is found within the immunogen sequence (93% positive by BLAST). Cross reactivity with SLIT-3 homologues from other sources has not been determined.
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アプリケーション
適用あり: WBmore details -
種交差性
交差種: Cow
交差が予測される動物種: Mouse, Rat, Chicken, Human -
免疫原
Synthetic peptide:
GKDSYVELASAKVR-C
conjugated to KLH, corresponding to amino acids 1164-1177 of Human Slit3. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.01% Sodium azide
Constituents: 0.424% Tripotassium orthophosphate, 0.88% Sodium chloride -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
This affinity purified antibody is directed against human SLIT-3 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab11018の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa).
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特記事項 |
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WB
1/500 - 1/2000. Detects a band of approximately 145 kDa (predicted molecular weight: 169 kDa). |
ターゲット情報
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機能
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors. -
組織特異性
Predominantly expressed in thyroid. -
配列類似性
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 9 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 20 LRR (leucine-rich) repeats.
Contains 4 LRRCT domains.
Contains 4 LRRNT domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 374173 Chicken
- Entrez Gene: 6586 Human
- Entrez Gene: 20564 Mouse
- Entrez Gene: 83467 Rat
- Omim: 603745 Human
- SwissProt: O75094 Human
- SwissProt: Q9WVB4 Mouse
- SwissProt: O88280 Rat
see all -
別名
- FLJ10764 antibody
- KIAA0814 antibody
- MEGF 5 antibody
see all
画像
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Anti-Slit3 antibody (ab11018) at 1/800 dilution + Bovine thyroid whole cell lysate at 35 µg
Secondary
Goat-anti-Rabbit IgG [H&L] at 1/10000 dilution
Predicted band size: 169 kDa
Observed band size: 145 kDa why is the actual band size different from the predicted?
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab11018 は 2 報の論文で使用されています。
- Kong Y et al. Slit-miR-218-Robo axis regulates retinal neovascularization. Int J Mol Med 37:1139-45 (2016). PubMed: 26935869
- Pi L et al. CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators. FASEB J : (2012). WB . PubMed: 22611085