Anti-SLC10A2/ASBT 抗体 (ab82170)
Key features and details
- Goat polyclonal to SLC10A2/ASBT
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-SLC10A2/ASBT antibody
SLC10A2/ASBT 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to SLC10A2/ASBT -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat -
免疫原
Synthetic peptide corresponding to Mouse SLC10A2/ASBT aa 337-348 (C terminal).
Sequence:C-DETNKGFQPDEK
Database link: NP_035518.1 -
ポジティブ・コントロール
- Mouse Small Intestine lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 0.5% Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab82170の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
特記事項 |
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WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 38 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. -
関連疾患
Defects in SLC10A2 are a cause of primary bile acid malabsorption (PBAM) [MIM:613291]. PBAM is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohepatic circulation of bile acids, and reduced plasma cholesterol levels. -
配列類似性
Belongs to the sodium:bile acid symporter family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 20494 Mouse
- Entrez Gene: 29500 Rat
- SwissProt: P70172 Mouse
- SwissProt: Q62633 Rat
- Unigene: 3500 Mouse
- Unigene: 85891 Rat
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別名
- Apical sodium dependent bile acid transporter antibody
- Apical sodium- dependent bile acid transporter antibody
- Apical sodium-dependent bile acid transporter antibody
see all
画像
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Anti-SLC10A2/ASBT antibody (ab82170) at 0.5 µg/ml + Mouse small intestine lysate in RIPA buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 38 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab82170 は 1 報の論文で使用されています。
- Jiang T et al. Linderae Radix Ethanol Extract Alleviates Diet-Induced Hyperlipidemia by Regulating Bile Acid Metabolism Through gut Microbiota. Front Pharmacol 12:627920 (2021). PubMed: 33679408