Anti-SHOX2 抗体 [1D1] (ab55740)
![Western blot - Anti-SHOX2 antibody [1D1] (ab55740)](https://www.abcam.co.jp/ps/products/55/ab55740/Images/ab55740-358926-anti-shox2-antibody-westernblot-recombinant-protein.jpg "Western blot - Anti-SHOX2 antibody [1D1] (ab55740)")
Key features and details
- Mouse monoclonal [1D1] to SHOX2
- Suitable for: WB, IHC-Fr
- Reacts with: Rat, Human, Recombinant fragment
- Isotype: IgG2a
製品の概要
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製品名
Anti-SHOX2 antibody [1D1]
SHOX2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [1D1] to SHOX2 -
由来種
Mouse -
アプリケーション
適用あり: WB, IHC-Frmore details -
種交差性
交差種: Rat, Human, Recombinant fragment -
免疫原
Recombinant fragment corresponding to Human SHOX2 aa 117-204.
Sequence:SPELKDRKDDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHK
Database link: O60902 -
ポジティブ･コントロール
- WB: Human liver tissue lysat; PC-12 cell lysate
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特記事項
This product was changed from ascites to tissue culture supernatant on 16/Oct/2019. Lot numbers higher than GR3303529 are from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: PBS -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
1D1 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab55740の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa.
|
|
| IHC-Fr | (1) |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa. |
|
IHC-Fr
Use at an assay dependent concentration. |
ターゲット情報
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機能
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. -
組織特異性
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta. -
配列類似性
Belongs to the paired homeobox family. Bicoid subfamily.
Contains 1 homeobox DNA-binding domain. -
発生段階
Expressed during cranofacial development as well as in heart. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 6474 Human
- Entrez Gene: 25546 Rat
- Omim: 602504 Human
- SwissProt: O60902 Human
- SwissProt: O35750 Rat
- Unigene: 55967 Human
- Unigene: 11258 Rat
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別名
- Homeobox protein Og12X antibody
- OG 12 antibody
- OG 12X antibody
see all
画像
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Western blot - Anti-SHOX2 antibody [1D1] (ab55740)Anti-SHOX2 antibody [1D1] (ab55740) + Recombinant SHOX2 Protein.
Predicted band size: 35 kDaThis image was generated using the ascites version of the product.
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![Western blot - Anti-SHOX2 antibody [1D1] (ab55740)](https://www.abcam.co.jp/ps/products/55/ab55740/Images/ab55740-69114-anti-shox2-antibody-western-blot.jpg)
Western blot - Anti-SHOX2 antibody [1D1] (ab55740)SHOX2 antibody (ab55740) at 1ug/lane + PC-12 cell lysate at 25ug/lane.
This image was generated using the ascites version of the product.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (17)
ab55740 は 17 報の論文で使用されています。
- Dai Y et al. Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes. Biol Open 12:N/A (2023). PubMed: 37272627
- Yin L et al. RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells. Stem Cell Res Ther 13:324 (2022). PubMed: 35851424
- Wiesinger A et al. A single cell transcriptional roadmap of human pacemaker cell differentiation. Elife 11:N/A (2022). PubMed: 36217819
- Li J et al. Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models. J Tissue Eng 13:20417314221127908 (2022). PubMed: 36277058
- Liu F et al. The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC. Int J Stem Cells 15:247-257 (2022). PubMed: 35220280
