Anti-SerpinB3/SCCA 抗体 (ab186842)
Key features and details
- Rabbit polyclonal to SerpinB3/SCCA
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SerpinB3/SCCA antibody
SerpinB3/SCCA 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SerpinB3/SCCA -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human SerpinB3/SCCA.
Database link: P29508 -
ポジティブ･コントロール
- HeLa, M21, H375, HepG2, 293T, SHSY-5Y and OVCAR3 cell extracts.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab186842の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 45 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 45 kDa. |
ターゲット情報
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機能
May act as a protease inhibitor to modulate the host immune response against tumor cells. -
組織特異性
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). -
配列類似性
Belongs to the serpin family. Ov-serpin subfamily. -
発生段階
Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. -
細胞内局在
Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level. - Information by UniProt
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参照データベース
- Entrez Gene: 6317 Human
- Omim: 600517 Human
- SwissProt: P29508 Human
- Unigene: 227948 Human
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別名
- HsT1196 antibody
- Protein T4 A antibody
- Protein T4-A antibody
see all
画像
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Western blot - Anti-SerpinB3/SCCA antibody (ab186842)All lanes : Anti-SerpinB3/SCCA antibody (ab186842) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : M21 cell extract
Lane 3 : H375 cell extract
Lane 4 : HepG2 cell extract
Lane 5 : 293T cell extract
Lane 6 : SHSY-5Y cell extract
Lane 7 : OVCAR3 cell extract
Predicted band size: 45 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab186842 は 1 報の論文で使用されています。
- Derakhshan S et al. Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa. J Appl Oral Sci 29:e20210374 (2021). PubMed: 34878006