Anti-SEMA3B 抗体 (ab48197)
Key features and details
- Rabbit polyclonal to SEMA3B
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-SEMA3B antibody -
製品の詳細
Rabbit polyclonal to SEMA3B -
由来種
Rabbit -
特異性
This antibody is specific for SEMA 3B. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Zebrafish
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免疫原
Synthetic peptide corresponding to Human SEMA3B aa 100-200.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: Tris glycine, 0.87% Sodium chloride -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab48197の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/5000 - 1/20000. Predicted molecular weight: 51, 83 kDa.
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| 特記事項 |
|---|
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WB
1/5000 - 1/20000. Predicted molecular weight: 51, 83 kDa. |
ターゲット情報
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機能
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. -
組織特異性
Expressed abundantly but differentially in a variety of neural and nonneural tissues. -
配列類似性
Belongs to the semaphorin family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 PSI domain.
Contains 1 Sema domain. -
細胞内局在
Secreted. Endoplasmic reticulum. Accumulates in the endoplasmic reticulum. - Information by UniProt
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参照データベース
- Entrez Gene: 20347 Mouse
- SwissProt: Q0VGP2 Mouse
- SwissProt: Q62177 Mouse
- Unigene: 4083 Mouse
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別名
- SEM3B_HUMAN antibody
- Sema A(V) antibody
- Sema V antibody
see all
画像
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Western blot - Anti-SEMA3B antibody (ab48197)Anti-SEMA3B antibody (ab48197) at 1/5000 dilution + mouse E16 cerebellum lysate
Developed using the ECL technique.
Predicted band size: 51, 83 kDa
Observed band size: 51,83 kDa why is the actual band size different from the predicted?
A band is seen at ~50 kDa, representing the secreted form of the protein and also a faint band at ~83 kDa, representing the pro-form of the protein.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (13)
ab48197 は 13 報の論文で使用されています。
- Kouri AM et al. Clinical and Histopathologic Characteristics of Pediatric Patients With Primary Membranous Nephropathy. Kidney Int Rep 8:2368-2375 (2023). PubMed: 38025223
- Iwakura T et al. Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan. Sci Rep 12:2967 (2022). PubMed: 35194125
- Du Y et al. Hippocampal semaphorin 3B improves depression-like behaviours in mice by upregulating synaptic plasticity and inhibiting neuronal apoptosis. J Neurochem 163:133-148 (2022). PubMed: 35892177
- Miller P et al. Clinicopathologic features of non-lupus membranous nephropathy in a pediatric population. Pediatr Nephrol 37:3127-3137 (2022). PubMed: 35333973
- Sethi S et al. Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients. Kidney Int 98:1253-1264 (2020). PubMed: 32534052