Anti-SEI-1 抗体 (ab154066)
Key features and details
- Rabbit polyclonal to SEI-1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SEI-1 antibody -
製品の詳細
Rabbit polyclonal to SEI-1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant fragment corresponding to Human SEI-1 aa 1-44 (N terminal).
Sequence:MLSKGLKRKR EEEEEKEPLA VDSWWLDPGH TAVAQAPPAV ASSS
Database link: Q9UHV2 -
ポジティブ・コントロール
- MOLT4 whole cell lysate; Human adrenal gland tumor tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 89.99% PBS, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154066の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 25 kDa.
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IHC-P |
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 25 kDa. |
IHC-P
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a). -
配列類似性
Contains 1 SERTA domain. - Information by UniProt
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参照データベース
- Entrez Gene: 539321 Cow
- Entrez Gene: 29950 Human
- Entrez Gene: 55942 Mouse
- Entrez Gene: 361526 Rat
- SwissProt: Q9UHV2 Human
- SwissProt: Q9JL10 Mouse
- Unigene: 269898 Human
- Unigene: 153684 Mouse
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別名
- CDK4 binding protein p34SEI antibody
- CDK4 binding protein p34SEI1 antibody
- CDK4-binding protein p34SEI1 antibody
see all
画像
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Anti-SEI-1 antibody (ab154066) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg
Predicted band size: 25 kDa
12% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SEI-1 antibody (ab154066)
Immunohistochemical analysis of paraffin embedded Human adrenal gland tumor tissue, labeling SEI-1 using ab154066 at 1/100 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab154066 は 2 報の論文で使用されています。
- Li J et al. Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway. Mol Cells 45:216-230 (2022). PubMed: 35014620
- Hu B et al. Sertad1 promotes prostate cancer progression through binding androgen receptor ligand binding domain. Int J Cancer 144:558-568 (2019). PubMed: 30230528