Anti-SCP1 抗体 (ab15090)
Key features and details
- Rabbit polyclonal to SCP1
- Suitable for: IHC-Fr, IHC-P, ICC/IF
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-SCP1 antibody
SCP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SCP1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Fr, IHC-P, ICC/IFmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide corresponding to Mouse SCP1 (C terminal).
Database link: Q62209 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: Tris citrate/phosphate -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab15090の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-Fr | (1) |
Use at an assay dependent concentration.
|
| IHC-P | (1) |
1/750.
|
| ICC/IF | (1) |
1/100 - 1/750.
|
| 特記事項 |
|---|
|
IHC-Fr
Use at an assay dependent concentration. |
|
IHC-P
1/750. |
|
ICC/IF
1/100 - 1/750. |
ターゲット情報
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機能
Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. -
組織特異性
Testis. -
ドメイン
Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity. -
細胞内局在
Nucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex. - Information by UniProt
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参照データベース
- Entrez Gene: 20957 Mouse
- SwissProt: Q62209 Mouse
- Unigene: 243849 Mouse
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別名
- Cancer/testis antigen 8 antibody
- CT8 antibody
- HOM TES 14 antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-SCP1 antibody (ab15090)SCP1 labeled in mouse pachytene preparation (red), using ab15090. CDK2 staining, near teleomeres, is also present (green).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SCP1 antibody (ab15090)Paraffin embeded IHC image of Murine SCP1 in mouse ovary using ab15090 at 1:750 dilution and secondary at 1:400.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (116)
ab15090 は 116 報の論文で使用されています。
- Crichton JH et al. Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nat Struct Mol Biol 30:188-199 (2023). PubMed: 36635604
- Zhao S et al. DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development. J Biol Chem 299:102905 (2023). PubMed: 36642183
- Huang T et al. SPIDR is required for homologous recombination during mammalian meiosis. Nucleic Acids Res 51:3855-3868 (2023). PubMed: 36938872
- He S et al. Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun 14:1715 (2023). PubMed: 36973253
- Lin H et al. The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis. Development 150:N/A (2023). PubMed: 37082953