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AB22055

Anti-SARS Envelope Protein 抗体 - Coronavirus

Anti-SARS Envelope Protein antibody - Coronavirus

4

(2 Reviews)

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(0 Publication)

Rabbit Polyclonal VEMP antibody. Suitable for WB and reacts with SARS-CoV samples.
1 Images
Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)
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Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (AB22055)

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Western blot - Anti-SARS Envelope Protein antibody - Coronavirus (ab22055) at 1 µg/mL

Observed band size: 16 kDa,32 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

SARS-CoV

アプリケーション

WB

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "SARS-CoV": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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製品の詳細

Applications overview

Tick: Tested and Guaranteed to work X: Will not work —: No data Reviews: Customers have been successful and shared their AbReview

<img src="https://www.abcam.com/ps/Products/22/ab22055/Images/ab22055-394526-applications-overview.jpg" height="125" width="675">

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.2% Gelatin
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The SARS Envelope Protein also known as E protein plays an essential role in the mechanical structure and function of the coronavirus. The protein has a mass of approximately 8.4 kDa and is expressed in the envelope of the virus. It functions as a viroporin creating ion channels that are important for the virus's lifecycle. These channels facilitate the transport of ions across the viral membrane contributing to the virus's assembly and budding processes.
Biological function summary

The SARS Envelope Protein exhibits significant functionality in viral pathogenesis and host interaction. It forms part of a larger protein complex in the viral envelope works alongside other structural proteins like the membrane (M) protein and nucleocapsid (N) protein. Through these actions the E protein influences coronavirus virulence assisting in virus-host interactions and the evasion of the host immune response.

Pathways

The SARS Envelope Protein actively participates in viral replication and assembly pathways. It interacts with host cell machinery to modulate viral and host processes important for replication. It also potentially influences the NF-kB signaling pathway which can affect host inflammation response. Related proteins include the spike (S) protein which helps the virus attach and enter host cells indicating a combined effort in infection spread.

The SARS Envelope Protein has a direct connection to illnesses such as COVID-19 and Severe Acute Respiratory Syndrome (SARS). The protein's role in viral assembly and immune evasion links it to the severity and transmission of these diseases. It is also connected to the IFN path where it can interfere with the host's interferon response a critical aspect of antiviral defense. These interactions make the SARS Envelope Protein a potential target for therapeutic interventions.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

See full target information SARS Envelope Protein
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Abcam product promise

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