Anti-SAP102 抗体 (ab3438)
Key features and details
- Rabbit polyclonal to SAP102
- Suitable for: IHC-Fr, WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-SAP102 antibody
SAP102 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SAP102 -
由来種
Rabbit -
特異性
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: IHC-Fr, WBmore details -
種交差性
交差種: Rat
交差が予測される動物種: Mouse, Human -
免疫原
Synthetic peptide corresponding to Rat SAP102 aa 83-100.
Sequence:GPVPPKPVPGKNTPKLNG
(Peptide available asab5841) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3438の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use a concentration of 10 µg/ml.
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WB | (2) |
Use a concentration of 3 µg/ml.
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特記事項 |
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IHC-Fr
Use a concentration of 10 µg/ml. |
WB
Use a concentration of 3 µg/ml. |
ターゲット情報
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機能
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. -
関連疾患
Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. -
配列類似性
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain. - Information by UniProt
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参照データベース
- Entrez Gene: 1741 Human
- Entrez Gene: 53310 Mouse
- Entrez Gene: 58948 Rat
- Omim: 300189 Human
- SwissProt: Q92796 Human
- SwissProt: P70175 Mouse
- SwissProt: Q62936 Rat
- Unigene: 726128 Human
see all -
別名
- bA291O7.3 antibody
- bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg antibody
- Discs large Drosophila homolog 3 antibody
see all
画像
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Western blot of SAP102 on extract from COS cells transfected with rat SAP102 using ab3438.
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Immunohistochemistry (Frozen sections) analysis of Ammon's Horn and the dentate gyrus of the rat hippocampus labeling SAP102 with ab3438.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab3438 は 5 報の論文で使用されています。
- Chen FB et al. LINC01315 Impairs microRNA-211-Dependent DLG3 Downregulation to Inhibit the Development of Oral Squamous Cell Carcinoma. Front Oncol 10:556084 (2020). PubMed: 33117688
- Deng HS et al. Phosphoproteomic profiling of oxycodone-treated spinal cord of rats with cancer-induced bone pain. Mol Med Rep 20:4695-4705 (2019). PubMed: 31702022
- Risher ML et al. Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood. Alcohol Clin Exp Res 39:989-97 (2015). PubMed: 25916839
- Rastaldi MP et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006). PubMed: 16585060
- Jensen TP et al. Expression of plasma membrane Ca2+ ATPase family members and associated synaptic proteins in acute and cultured organotypic hippocampal slices from rat. Brain Res Dev Brain Res 152:129-36 (2004). WB ; Rat . PubMed: 15351500