AB157125

Anti-RPS9 抗体

Name: Anti-RPS9 抗体 (ab157125) | Abcam
Brand: Abcam Limited
SKU: AB157125
Price: 73000 JPY
Availability: InStock

Anti-RPS9 antibody

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(1 Publication)

Rabbit Polyclonal RPS9 antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human 40S ribosomal protein S9 aa 1-50.

別名を表示する

Small ribosomal subunit protein uS4, 40S ribosomal protein S9, RPS9

1 Images

Unknown

Western blot - Anti-RPS9 antibody (AB157125)

All lanes:

Western blot - Anti-RPS9 antibody (ab157125) at 0.4 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

293T whole cell lysate at 50 µg

Lane 4:

Jurkat whole cell lysate at 50 µg

Lane 5:

NIH 3T3 whole cell lysate at 50 µg

Predicted band size: 23 kDa

true

Exposure time: 30s

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human, Mouse

アプリケーション

applications

免疫原

Synthetic Peptide within Human 40S ribosomal protein S9 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P46781

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chinese hamster": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Common marmoset": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Fish": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Lizard": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Zebra finch": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

精製に関する特記事項

ab157125 is affinity purified using an epitope specific to RPS9 immobilized on solid support.

バッファー組成

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

+4°C

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

RPS9 also known as Ribosomal Protein S9 plays an important role in protein synthesis by being part of the small 40S ribosomal subunit. It has a molecular mass of approximately 22 kDa. This protein is expressed in various tissues throughout the body and is essential for ribosome function. Its primary mechanical function involves the formation of ribosomes which are key components in the translation process translating the genetic code into proteins.

Biological function summary

As a component of the ribosomal assembly RPS9 is essential for maintaining the structure and function of ribosomes. It forms a part of the ribonucleoprotein complex that ensures the fidelity and accuracy of mRNA translation during protein synthesis. This activity is vital for cell growth and proliferation as it directly influences protein production efficiency. Any disruptions in this process can lead to misfolded proteins or incomplete translations affecting cell functionality.

Pathways

The function of RPS9 is critical in the mRNA processing and translation pathways. It associates closely with other ribosomal proteins such as RPS3 and RPL11 participating in the synthesis and processing of proteins required for various cellular activities. This involvement impacts key pathways like the mTOR signaling pathway which controls cell growth and metabolism and the p53 signaling pathway which is involved in cell cycle regulation and stress responses.

The role of RPS9 implicates it in cancer and Diamond-Blackfan anemia. Mutations or dysregulation of RPS9 can lead to abnormal cell proliferation contributing to oncogenesis. RPS9 has connections with the p53 protein pathway which plays a significant role in tumorigenesis when mutated or impaired. In Diamond-Blackfan anemia defects in ribosomal protein function including that of RPS9 result in bone marrow failure and defective erythropoiesis affecting red blood cell production.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Component of the small ribosomal subunit (PubMed : 23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed : 34516797).

See full target information 40S ribosomal protein S9

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer science 114:1464-1478 PubMed36601865

2023

Downregulated mitochondrial transcription factor A enhances mycoplasma infection to promote the metastasis of hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yinping Wang,Gang Wang,Xin Hong,Jing Zhao,Dan Wu,Lin Chen,Xiaoli Liu,Deyu Kong,Qichao Huang,Jinliang Xing,Nan Wang,Yilin Zhao

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RPS9 抗体

Anti-RPS9 antibody

Western blot - Anti-RPS9 antibody (AB157125)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

精製に関する特記事項

バッファー組成

出荷温度

短期保存温度

長期保存温度

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (1)

代替製品

Primary Antibodies

組合せ製品

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise