AB228542

Anti-RPL37 抗体

Anti-RPL37 antibody

JP Deleterious:医薬用外劇物

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(2 Publications)

Rabbit Polyclonal RPL37 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human 60S ribosomal protein L37.

別名を表示する

Large ribosomal subunit protein eL37, 60S ribosomal protein L37, G1.16, RPL37

3 Images

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for RPL37 (green) using ab228542 at 1/500 dilution in ICC/IF. Cells were fixed in 4% paraformaldehyde at RT for 15 minutes. Blue : Hoechst 33342.

Supplier Data

Western blot - Anti-RPL37 antibody (AB228542)

15% SDS-PAGE

All lanes:

Western blot - Anti-RPL37 antibody (ab228542) at 1/1000 dilution

Lane 1:

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 30 µg

Lane 2:

HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 30 µg

Predicted band size: 11 kDa

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Supplier Data

Western blot - Anti-RPL37 antibody (AB228542)

15% SDS-PAGE

All lanes:

Western blot - Anti-RPL37 antibody (ab228542) at 1/1000 dilution

Lane 1:

Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate at 30 µg

Lane 2:

Raji (human Burkitt's lymphoma cell line) whole cell lysate at 30 µg

Lane 3:

NCI-H929 whole cell lysate at 30 µg

Predicted band size: 11 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

WB, ICC/IF

applications

免疫原

Synthetic Peptide within Human 60S ribosomal protein L37. The exact immunogen used to generate this antibody is proprietary information.

P61927

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

バッファー組成

pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

RPL37 also known as ribosomal protein L37 is a component of the 60S subunit of eukaryotic ribosomes. The protein possesses a molecular mass of approximately 11 kDa. It is expressed in various tissues throughout the body and plays a fundamental role in protein synthesis. RPL37 binds to rRNA and is involved in the assembly and structural stability of the ribosomal unit facilitating the translation process during protein expression.

Biological function summary

Ribosomal protein L37 is essential in the formation and function of ribosome complexes. It is part of the large ribosomal subunit that contributes to stabilizing the interactions between the rRNA and the mRNA-tRNA complex during translation. The precise positioning of these molecules by RPL37 helps ensure accurate decoding of mRNA into polypeptide chains highlighting its role in efficient protein production within cells.

Pathways

RPL37 is implicated in the intricate mechanics of the ribosomal biogenesis and translation pathways. Within these pathways it cooperates with other ribosomal proteins such as RPL5 and RPL10 which also form part of the large ribosomal subunit. Together they enable the step-wise assembly and function of ribosomes ultimately impacting cellular growth and proliferation through protein synthesis.

Mutations or dysregulation of RPL37 can relate to various conditions such as cancer and Diamond-Blackfan anemia. In cancer aberrant expression of RPL37 has been connected to altered ribosome function impacting cell cycle progression and growth. Additionally in Diamond-Blackfan anemia RPL37 mutations can associate with disturbed ribosomal biogenesis leading to insufficient erythrocyte production. Associated proteins such as RPL11 and RPL15 may also show altered expression in these conditions further complicating the cellular environment.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).

See full target information 60S ribosomal protein L37

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 16:1580986 PubMed41019085

2025

Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhaokai Zhou,Yajun Chen,Zhan Wang,Shuai Yang,Zhengrui Li,Run Shi,Ruizhi Wang,Kui Liu,Xiaojuan Tang,Qi Li,Ran Xu

iScience 25:105366 PubMed36339258

2022

Single-cell RNA-seq transcriptomic landscape of human and mouse islets and pathological alterations of diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Chen,Junqing Zhang,Youyuan Huang,Xiaodong Tian,Yinmo Yang,Aimei Dong

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RPL37 抗体

Anti-RPL37 antibody

Immunocytochemistry/ Immunofluorescence - Anti-RPL37 antibody (AB228542)

Western blot - Anti-RPL37 antibody (AB228542)

Western blot - Anti-RPL37 antibody (AB228542)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (2)

組合せ製品

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise