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AB67196

Anti-RPL29 抗体

Anti-RPL29 antibody

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(3 Publications)

Mouse Polyclonal RPL29 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RPL29.

別名を表示する

Large ribosomal subunit protein eL29, 60S ribosomal protein L29, Cell surface heparin-binding protein HIP, RPL29

2 Images
Western blot - Anti-RPL29 antibody (AB67196)
  • WB

Unknown

Western blot - Anti-RPL29 antibody (AB67196)

All lanes:

Western blot - Anti-RPL29 antibody (ab67196) at 1/500 dilution

Lane 1:

RPL29 transfected 293T cell lysate at 25 µg/mL

Lane 2:

Non transfected 293T cell lysate at 25 µg/mL

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Predicted band size: 18 kDa

Observed band size: 25 kDa

false

Western blot - Anti-RPL29 antibody (AB67196)
  • WB

Unknown

Western blot - Anti-RPL29 antibody (AB67196)

All lanes:

Western blot - Anti-RPL29 antibody (ab67196) at 1/500 dilution

All lanes:

human pancreas tissue lysate at 25 µg/mL

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Predicted band size: 18 kDa

Observed band size: 21 kDa

false

Key facts

宿主種

Mouse

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

Yes

交差種

Human

アプリケーション

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human RPL29.

P47914

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

RPL29 also known as ribosomal protein L29 is a structural component of the large 60S ribosomal subunit. It has a molecular mass of approximately 17 kDa. This protein contributes to ribosome function by connecting with rRNA and other ribosomal proteins to aid protein synthesis. RPL29 shows strong expression in tissues with high protein turnover such as the liver and pancreas where efficient protein production is necessary for maintaining cellular functions.
Biological function summary

RPL29 takes part in the assembly of the ribosome which is essential for the translation process in protein synthesis. It is not found alone; instead it becomes integrated into the large ribosomal subunit. This integration is critical for the assembly and stability of the ribosomal structure. Without proper RPL29 incorporation ribosome function and consequently cellular protein synthesis can become impaired.

Pathways

The ribosomal protein RPL29 plays important roles in both the translation and ribosome biogenesis pathways. It functions alongside other ribosomal proteins like RPL5 and RPL11 in these pathways to ensure correct assembly and functionality of ribosomes. Ribosome biogenesis is a highly-regulated process that starts in the nucleolus and extends into the cytoplasm involving steps important for cell growth and division.

Mutations or dysregulation in RPL29 have been linked with certain types of cancers such as colorectal carcinoma. Cancerous cells often exhibit altered ribosomal function to support their increased need for protein synthesis. RPL29’s interaction with other ribosomal proteins like RPL11 affects ribosomal stress responses which can impact cancer progression. Additionally aberrations in ribosome function where RPL29 is a player are associated with ribosomopathies a group of disorders characterized by defective ribosome biogenesis and function.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Component of the large ribosomal subunit (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547).
See full target information RPL29
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文献 (3)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 300:107877 PubMed39395807

2024

O-GlcNAcylation of ribosome-associated proteins is concomitant with translational reprogramming during proteotoxic stress.

Applications

Unspecified application

Species

Unspecified reactive species

Quira Zeidan,Jie L Tian,Junfeng Ma,Farzad Eslami,Gerald W Hart

Frontiers in oncology 11:681366 PubMed34136404

2021

N-Myristoylation by NMT1 Is POTEE-Dependent to Stimulate Liver Tumorigenesis Differentially Regulating Ubiquitination of Targets.

Applications

Unspecified application

Species

Unspecified reactive species

Guoqing Zhu,Feng Wang,Haojie Li,Xiao Zhang,Qi Wu,Ya Liu,Mingping Qian,Susu Guo,Yueyue Yang,Xiangfei Xue,Fenyong Sun,Yongxia Qiao,Qiuhui Pan

Arthritis and rheumatism 62:2673-9 PubMed20496420

2010

Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.

Applications

Unspecified application

Species

Unspecified reactive species

Michel Neidhart,Emmanuel Karouzakis,Gerald G Schumann,Renate E Gay,Steffen Gay
View all publications
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