AB193164

Anti-RPL28 抗体

Name: Anti-RPL28 抗体 (ab193164) | Abcam
Brand: Abcam Limited
SKU: AB193164
Price: 70000 JPY
Availability: InStock

Anti-RPL28 antibody

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(2 Publications)

Rabbit Polyclonal RPL28 antibody. Suitable for ICC, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RPL28.

別名を表示する

Large ribosomal subunit protein eL28, 60S ribosomal protein L28, RPL28

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pancreatic tissue labelling RPL28 with ab193164 at a dilution of 1/100.

Supplier Data

Immunocytochemistry - Anti-RPL28 antibody (AB193164)

Immunocytochemistry analysis of HepG2 (Human liver hepatocellular carcinoma cell line) cells labeling RPL28 with ab193164 at dilution of 1/100.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian cancer tissue labeling RPL28 with ab193164 at 1/100 dilution.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

ICC, IHC-P

applications

免疫原

Recombinant Full Length Protein corresponding to Human RPL28.

P46779

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein G

精製に関する特記事項

>95%

バッファー組成

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The ribosomal protein L28 (RPL28) also known as 60S ribosomal protein L28 plays a mechanical role in the formation of ribosomes which are essential for protein synthesis. RPL28 forms part of the large 60S subunit of the ribosome. This protein has a molecular mass of approximately 15-17 kDa and is expressed in various tissues due to its fundamental role in cellular functions. The expression of RPL28 occurs widely but can change in response to cellular activity related to protein production needs.

Biological function summary

RPL28 participates in the assembly and function of ribosomes within the cell. It acts as a structural component of the ribosomal large subunit and therefore helps in the synthesis of proteins by translating mRNA. As part of the ribosomal complex RPL28 ensures the proper alignment of rRNA and tRNA during protein assembly. Its function is integral to the ribosome's role in facilitating correct translation steps needed for cellular protein production.

Pathways

RPL28 has important roles in the protein synthesis (translation) and ribosome biogenesis pathways. It interacts with other ribosomal proteins and factors involved in these pathways. RPL28 coordinates with proteins such as RPL5 and RPL11 which are also involved in the assembly of the large ribosomal subunit and ensure effective translation and synthesis of proteins required by the cell.

Mutations or alterations in RPL28 expression have connections to disorders of ribosome dysfunction known as ribosomopathies. Such conditions may include Diamond-Blackfan Anemia where ribosomal biogenesis is impaired possibly involving other proteins like RPL5. Deficiencies in RPL28 or associated proteins can lead to abnormal ribosome assembly affecting protein synthesis and contributing to disease symptoms.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Component of the large ribosomal subunit (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 12962325, PubMed : 23636399, PubMed : 32669547).

See full target information RPL28

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Metabolites 15: PubMed40710572

2025

Aerobic Exercise Delays Age-Related Sarcopenia in Mice via Alleviating Imbalance in Mitochondrial Quality Control.

Applications

Unspecified application

Species

Unspecified reactive species

Danlin Zhu,Lian Wang,Haoyang Gao,Ze Wang,Ke Li,Xiaotong Ma,Linlin Zhao,Weihua Xiao

Cell reports 41:111571 PubMed36323262

2022

Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Katherine M Hannan,Priscilla Soo,Mei S Wong,Justine K Lee,Nadine Hein,Perlita Poh,Kira D Wysoke,Tobias D Williams,Christian Montellese,Lorey K Smith,Sheren J Al-Obaidi,Lorena Núñez-Villacís,Megan Pavy,Jin-Shu He,Kate M Parsons,Karagh E Loring,Tess Morrison,Jeannine Diesch,Gaetan Burgio,Rita Ferreira,Zhi-Ping Feng,Cathryn M Gould,Piyush B Madhamshettiwar,Johan Flygare,Thomas J Gonda,Kaylene J Simpson,Ulrike Kutay,Richard B Pearson,Christoph Engel,Nicholas J Watkins,Ross D Hannan,Amee J George

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-RPL28 抗体

Anti-RPL28 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Immunocytochemistry - Anti-RPL28 antibody (AB193164)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL28 antibody (AB193164)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

精製に関する特記事項

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (2)

代替製品

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise