Anti-RPC39 抗体 (ab76951)
Key features and details
- Rabbit polyclonal to RPC39
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RPC39 antibody
RPC39 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to RPC39 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human RPC39 (N terminal).
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ポジティブ･コントロール
- Human brain tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab76951の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 36 kDa.
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| ICC/IF |
Use a concentration of 20 µg/ml.
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| IHC-P |
Use a concentration of 2.5 µg/ml.
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| 特記事項 |
|---|
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WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 36 kDa. |
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ICC/IF
Use a concentration of 20 µg/ml. |
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IHC-P
Use a concentration of 2.5 µg/ml. |
ターゲット情報
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機能
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. -
配列類似性
Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 10621 Human
- SwissProt: Q9H1D9 Human
- Unigene: 472227 Human
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別名
- DNA directed RNA polymerase III 39 kDa polypeptide antibody
- DNA directed RNA polymerase III 39 kDa polypeptide F antibody
- DNA directed RNA polymerase III subunit F antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-RPC39 antibody (ab76951)
Immunofluorescence of RPC39 in Human brain tissue with ab76951 at 20 ug/mL.
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Western blot - Anti-RPC39 antibody (ab76951)Lane 1 : Anti-RPC39 antibody (ab76951) at 0.5 µg/ml
Lane 2 : Anti-RPC39 antibody (ab76951) at 1 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 36 kDa
Observed band size: 35 kDa why is the actual band size different from the predicted? -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPC39 antibody (ab76951)ab76951 at 2.5µg/ml staining RPC39 in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab76951 は論文での使用が確認できていません。