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AB187657

Anti-ROR beta/RORB 抗体 [EPR15552] - N-terminal

Anti-ROR beta/RORB antibody [EPR15552] - N-terminal

4

(1 Review)

|

(3 Publications)

Rabbit Recombinant Monoclonal ROR beta/RORB antibody. N-terminal. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 3 publications.

別名を表示する

NR1F2, RZRB, RORB, Nuclear receptor ROR-beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, Retinoid-related orphan receptor-beta

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)

Immunofluorescent analysis of 100% methanol-fixed, 0.1% TritonX-100 permeabilized HepG2 (human hepatocellular carcinoma epithelial cell) labelling ROR beta/RORB with ab187657 at 1/500 dilution, followed by Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488 (ab150077) secondary antibody at 1/1000 dilution (green).

Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker (Alexa Fluor® 594) (ab195889) at 1/200 dilution was used as a counterstain (red).

The nuclear counterstain is DAPI (blue).

Confocal image showing nuclear staining in HepG2 cell line. Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)
  • WB

Supplier Data

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)

All lanes:

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (ab187657) at 1/1000 dilution

All lanes:

Human cerebellum tissue lysate at 10 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 33 kDa,53 kDa

false

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)
  • WB

Supplier Data

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (AB187657)

All lanes:

Western blot - Anti-ROR beta/RORB antibody [EPR15552] - N-terminal (ab187657) at 1/1000 dilution

All lanes:

HepG2 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 53 kDa

false

関連する標識済み抗体及び組成の異なる製品 (1)

  • Carrier free

    Anti-ROR beta/RORB antibody [EPR15552] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR15552

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

ICC/IF, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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代替製品

Primary Antibodies

AB154889

Anti-ROR beta/RORB antibody

Western blot - Anti-ROR beta/RORB antibody (AB154889)

  • 0
  • 0
Primary Antibodies

AB228650

Anti-ROR beta/RORB antibody

Western blot - Anti-ROR beta/RORB antibody (AB228650)

  • 0
  • 0
Primary Antibodies

AB188756

Anti-ROR beta/RORB antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ROR beta/RORB antibody (AB188756)

  • 1
  • 2

組合せ製品

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Primary Antibodies

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Primary Antibodies

AB92446

Anti-SATB2 antibody [EPNCIR130A]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SATB2 antibody [EPNCIR130A] (AB92446)

  • 5
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "notRecommended", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "1/1000", "ICCIF-species-notes": "<p></p>" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Conditional Ambient
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity).. Isoform 1 is critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina. Regulates the expression of PTF1A synergistically with FOXN4 (By similarity).
See full target information RORB
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文献 (3)

Recent publications for all applications. Explore the full list and refine your search

eLife 13: PubMed40762561

2025

The novel role of Kallistatin in linking metabolic syndromes and cognitive memory deterioration by inducing amyloid-β plaques accumulation and tau protein hyperphosphorylation.

Applications

Unspecified application

Species

Unspecified reactive species

Weiwei Qi,Yanlan Long,Ziming Li,Zhen Zhao,Jinhui Shi,Wanting Xie,Laijian Wang,Yandan Tan,Ti Zhou,Minting Liang,Ping Jiang,Bin Jiang,Xia Yang,Guoquan Gao

iScience 26:108306 PubMed38026209

2023

Preclinical long-term safety of intraspinal transplantation of human dorsal spinal GABA neural progenitor cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaolong Zheng,Zhixian Liu,Ziyu He,Jia Xu,YaNan Wang,ChenZi Gong,Ruoying Zhang,Su-Chun Zhang,Hong Chen,Wei Wang

Evidence-based complementary and alternative medicine : eCAM 2022:1459232 PubMed36034952

2022

Bufei Decoction Improves Lung-Qi Deficiency Syndrome of Chronic Obstructive Pulmonary Disease in Rats by Regulating the Balance of Th17/Treg Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Junxi Shen,Xing Zhu,Yunzhi Chen,Wen Li,Huaiquan Liu,Cancan Chu,Yu Zhang,Changjun Xu,Pingzhen Tong,Xinran Yu,Guangyong Yang,Ying Deng
View all publications
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Abcam product promise

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