Anti-RNF36 抗体 [EPR4755] (ab111943)
![Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.co.jp/ps/products/111/ab111943/Images/ab111943-125197-anti-rnf36-antibody-epr4755-western-blot.jpg "Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4755] to RNF36
- Suitable for: WB
- Reacts with: Mouse, Human
Related conjugates and formulations
製品の概要
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製品名
Anti-RNF36 antibody [EPR4755]
RNF36 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR4755] to RNF36 -
由来種
Rabbit -
特異性
ab111943 detects at least 4 isoforms. -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human testis and Neuro-2a cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR4755 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab111943の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa).
|
| 特記事項 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa). |
追加情報
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
ターゲット情報
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機能
May play a role in apoptosis. -
配列類似性
Belongs to the TRIM/RBCC family.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger. -
翻訳後修飾
Phosphorylated. Phosphorylation is necessary for nuclear localization. -
細胞内局在
Nucleus speckle. - Information by UniProt
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参照データベース
- Entrez Gene: 140691 Human
- Entrez Gene: 70928 Mouse
- Entrez Gene: 311373 Rat
- SwissProt: Q86WT6 Human
- SwissProt: Q80X56 Mouse
- SwissProt: Q5BK82 Rat
- Unigene: 489254 Human
- Unigene: 379188 Mouse
see all -
別名
- E3 ubiquitin protein ligase TRIM69 antibody
- HSD34 antibody
- RFP like domain containing protein trimless antibody
see all
画像
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Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)Anti-RNF36 antibody [EPR4755] (ab111943) at 1/1000 dilution + Human testis lysate at 10 µg
Predicted band size: 57 kDa -
![Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.co.jp/ps/products/111/ab111943/Images/ab111943-125196-anti-rnf36-antibody-epr4755-western-blot.jpg)
Western blot - Anti-RNF36 antibody [EPR4755] (ab111943)Anti-RNF36 antibody [EPR4755] (ab111943) at 1/1000 dilution + Neuro-2a cell lysate at 10 µg
Predicted band size: 57 kDa -
![Anti-RNF36 antibody [EPR4755] (ab111943)](https://www.abcam.co.jp/ps/products/111/ab111943/Images/ab111943-3-benefits-of-recombinant-antibodies.png)
Anti-RNF36 antibody [EPR4755] (ab111943)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab111943 は 4 報の論文で使用されています。
- Jia Y et al. Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis. J Cancer 14:200-218 (2023). PubMed: 36741265
- Rihn SJ et al. TRIM69 Inhibits Vesicular Stomatitis Indiana Virus. J Virol 93:N/A (2019). PubMed: 31375575
- Rong X et al. TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox Biol 22:101157 (2019). PubMed: 30844644
- Wang K et al. Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3. PLoS Pathog 14:e1007287 (2018). PubMed: 30142214