Anti-RNase 7 抗体 [CL0224] (ab154143)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)](https://www.abcam.co.jp/ps/products/154/ab154143/Images/Ribonuclease-7-Primary-antibodies-ab154143-1.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)")
Key features and details
- Mouse monoclonal [CL0224] to RNase 7
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-RNase 7 antibody [CL0224]
RNase 7 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CL0224] to RNase 7 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human RNase 7 aa 31-155.
Sequence:KGMTSSQWFKIQHMQPSPQACNSAMKNINKHTKRCKDLNTFLHEPFSSVA ATCQTPKIACKNGDKNCHQSHGPVSLTMCKLTSGKYPNCRYKEKRQNKSY VVACKPPQKKDSQQFHLVPVHLDRV
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ポジティブ･コントロール
- Human skin, kidney and fallopian tube tissues; RNase 7 over-expression HEK293T lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
CL0224 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154143の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. -
組織特異性
Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart. -
配列類似性
Belongs to the pancreatic ribonuclease family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 84659 Human
- Omim: 612484 Human
- SwissProt: Q9H1E1 Human
- Unigene: 525206 Human
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別名
- EC 3.1.27.- antibody
- MGC133220 antibody
- Ribonuclease 7 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)
Immunohistochemical analysis of Human skin tissue labeling RNase 7 with ab154143 at 1/50 dilution.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)](https://www.abcam.co.jp/ps/products/154/ab154143/Images/Ribonuclease-7-Primary-antibodies-ab154143-2.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)Immunohistochemical analysis of Human kidney tissue labeling RNase 7 with ab154143 at 1/50 dilution.
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)](https://www.abcam.co.jp/ps/products/154/ab154143/Images/Ribonuclease-7-Primary-antibodies-ab154143-3.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RNase 7 antibody [CL0224] (ab154143)Immunohistochemical analysis of Human fallopian tube tissue labeling RNase 7 with ab154143 at 1/50 dilution.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab154143 は 2 報の論文で使用されています。
- Neopane P et al. Immunohistochemical Localization of RNase 7 in Normal and Inflamed Oral Epithelia and Salivary Glands. Acta Histochem Cytochem 52:35-43 (2019). PubMed: 31341339
- Patra V et al. Unique profile of antimicrobial peptide expression in polymorphic light eruption lesions compared to healthy skin, atopic dermatitis, and psoriasis. Photodermatol Photoimmunol Photomed 34:137-144 (2018). IHC-P ; Human . PubMed: 29044786