Anti-RIN1 (phospho S351) 抗体 [EPR2734(2)] (ab172976)
![Western blot - Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976)](https://www.abcam.co.jp/ps/products/172/ab172976/Images/ab172976-196100-anti-rin1-phospho-s351-antibody-epr27342-western-blot.jpg "Western blot - Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR2734(2)] to RIN1 (phospho S351)
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-RIN1 (phospho S351) antibody [EPR2734(2)]
RIN1 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR2734(2)] to RIN1 (phospho S351) -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- HeLa cell lysate, treated with Okadaic Acid and Calyculin A.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR2734(2) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab172976の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/10000 - 1/50000. Detects a band of approximately 90 kDa (predicted molecular weight: 84 kDa).
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| 特記事項 |
|---|
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WB
1/10000 - 1/50000. Detects a band of approximately 90 kDa (predicted molecular weight: 84 kDa). |
追加情報
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
ターゲット情報
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関連性
RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer. -
細胞内局在
Cytoplasmic and Plasma membrane -
参照データベース
- Entrez Gene: 9610 Human
- Omim: 605965 Human
- SwissProt: Q13671 Human
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別名
- Ras and Rab interactor 1 antibody
- ras inhibitor 1 antibody
- ras inhibitor antibody
see all
画像
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Western blot - Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976)All lanes : Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976) at 10000 µg/ml
Lane 1 : HeLa cell lysate, untreated
Lane 2 : HeLa cell lysate, treated with Okadaic Acid and Calyculin A
Lysates/proteins at 10 µg per lane.
Predicted band size: 84 kDa -
![Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976)](https://www.abcam.co.jp/ps/products/172/ab172976/Images/ab172976-2-benefits-of-recombinant-antibodies.png)
Anti-RIN1 (phospho S351) antibody [EPR2734(2)] (ab172976)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab172976 は論文での使用が確認できていません。