Anti-RGS1 抗体 (ab154973)
Key features and details
- Rabbit polyclonal to RGS1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RGS1 antibody
RGS1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to RGS1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cow
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免疫原
Recombinant fragment, corresponding to a region within amino acids 1-209 of Human RGS1 (UniProt Q08116).
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ポジティブ･コントロール
- K562 cell lysate; Human Cal27 xenograft tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154973の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 24 kDa.
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| IHC-P |
1/100 - 1/1000.
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| 特記事項 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 24 kDa. |
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IHC-P
1/100 - 1/1000. |
ターゲット情報
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機能
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. -
組織特異性
B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high. -
配列類似性
Contains 1 RGS domain. -
翻訳後修飾
Could be phosphorylated. Might be functionally regulated by protein kinase(s). - Information by UniProt
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参照データベース
- Entrez Gene: 5996 Human
- Entrez Gene: 50778 Mouse
- Omim: 600323 Human
- SwissProt: Q08116 Human
- SwissProt: Q9JL25 Mouse
- Unigene: 75256 Human
- Unigene: 103701 Mouse
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別名
- 1R20 antibody
- B cell activation protein BL34 antibody
- B-cell activation protein BL34 antibody
see all
画像
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Western blot - Anti-RGS1 antibody (ab154973)Anti-RGS1 antibody (ab154973) at 1/1000 dilution + K562 whole cell lysate at 30 µg
Predicted band size: 24 kDa
12% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RGS1 antibody (ab154973)Immunohistochemical analysis of paraffin-embedded Human Cal27 xenograft tissue labeling RGS1 with ab154973 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab154973 は 1 報の論文で使用されています。
- Zhang L et al. MicroRNA-376b-3p targets RGS1 mRNA to inhibit proliferation, metastasis, and apoptosis in osteosarcoma. Ann Transl Med 9:1652 (2021). PubMed: 34988161