Anti-Respiratory Syncytial Virus 抗体 [2F7] (ab43812)
![Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)](https://www.abcam.co.jp/ps/products/43/ab43812/Images/ab43812-264031-anti-respiratory-syncytial-virus-antibody-2f7-immunofluorescence.jpg "Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)")
Key features and details
- Mouse monoclonal [2F7] to Respiratory Syncytial Virus
- Suitable for: WB, IHC-Fr, ICC/IF, ELISA
- Reacts with: Respiratory syncytial virus
- Isotype: IgG1
製品の概要
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製品名
Anti-Respiratory Syncytial Virus antibody [2F7]
Respiratory Syncytial Virus 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2F7] to Respiratory Syncytial Virus -
由来種
Mouse -
アプリケーション
適用あり: WB, IHC-Fr, ICC/IF, ELISAmore details -
種交差性
交差種: Respiratory syncytial virus -
免疫原
Recombinant FP
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
2F7 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab43812の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/5000. Predicted molecular weight: 48 , 70 kDa.
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| IHC-Fr |
1/100 - 1/500.
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| ICC/IF |
1/100 - 1/500.
Immunocytology on infected cells. |
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| ELISA |
1/1000 - 1/2000.
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| 特記事項 |
|---|
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WB
1/500 - 1/5000. Predicted molecular weight: 48 , 70 kDa. |
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IHC-Fr
1/100 - 1/500. |
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ICC/IF
1/100 - 1/500. Immunocytology on infected cells. |
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ELISA
1/1000 - 1/2000. |
ターゲット情報
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関連性
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. -
細胞内局在
Virion. Host cytoplasm -
参照データベース
- Entrez Gene: 2829063 Respiratory syncytial virus
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別名
- RS virus antibody
- RSV antibody
画像
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Immunocytochemistry/ Immunofluorescence - Anti-Respiratory Syncytial Virus antibody [2F7] (ab43812)Image from Krzyzaniak MA et al., PLoS Pathogens. 2013;9(4):e1003309. Fig 2.; doi: 10.1371/journal.ppat.1003309 Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/
Immunofluorescent staining of Respiratory Syncytial Virus F protein Bound to HeLa cells using ab43812. Respiratory Syncytial Virus F protein was visualized in green and Respiratory Syncytial N protein in red.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (19)
ab43812 は 19 報の論文で使用されています。
- Talukdar SN et al. RSV-induced expanded ciliated cells contribute to bronchial wall thickening. Virus Res 327:199060 (2023). PubMed: 36746339
- Grabowski F et al. Antagonism between viral infection and innate immunity at the single-cell level. PLoS Pathog 19:e1011597 (2023). PubMed: 37669278
- Francese R et al. Identification of a βCD-Based Hyper-Branched Negatively Charged Polymer as HSV-2 and RSV Inhibitor. Int J Mol Sci 23:N/A (2022). PubMed: 35955832
- Czerkies M et al. Respiratory Syncytial Virus Protects Bystander Cells against Influenza A Virus Infection by Triggering Secretion of Type I and Type III Interferons. J Virol 96:e0134122 (2022). PubMed: 36326278
- Liu X et al. Human parainfluenza virus type 3 expressing the respiratory syncytial virus pre-fusion F protein modified for virion packaging yields protective intranasal vaccine candidates. PLoS One 15:e0228572 (2020). PubMed: 32045432