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AB243296

redFluor™ 710 Anti-CD3 抗体 [OKT3]

redFluor™ 710 Anti-CD3 antibody [OKT3]

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(1 Publication)

Anti-CD3 antibody [OKT3] conjugated to redFluor™ 710 - suitable for flow cytometry, and reacts with human samples. Clone [OKT3] is a mouse monoclonal antibody and one of the most commonly used clones for flow cytometry.

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別名を表示する

CD3d, T3D, CD3D, T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain

1 Images
Flow Cytometry - redFluor™ 710 Anti-CD3 antibody [OKT3] (AB243296)
  • Flow Cyt

Supplier Data

Flow Cytometry - redFluor™ 710 Anti-CD3 antibody [OKT3] (AB243296)

Flow cytometric analysis of human peripheral blood lymphocytes stained for CD3 with 5 μL (1 μg) ab243296 (solid line) or 1 μg redFluor™ 710 Mouse IgG2a isotype control (dashed line).

関連する標識済み抗体及び組成の異なる製品 (1)

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    APC Anti-CD3 epsilon antibody [OKT3]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

OKT3

アイソタイプ

IgG2a

軽鎖のタイプ

kappa

標識

redFluor™ 710

励起波長/蛍光波長

Ex: 684nm, Em: 704nm

キャリアフリー

No

交差種

Human

アプリケーション

Flow Cyt

applications

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代替製品

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Primary Antibodies

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Primary Antibodies

AB245731

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Primary Antibodies

AB5690

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  • 4
  • 46
Primary Antibodies

AB253269

Alexa Fluor® 647 Anti-CD3 antibody [OKT3]

Lab Essentials

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  • 0
  • 0

組合せ製品

Primary Antibodies

AB305048

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [CAL66] (AB305048)

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Primary Antibodies

AB200315

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Primary Antibodies

AB196147

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Primary Antibodies

AB237456

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p></p>" }, "Chimpanzee": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification
精製に関する特記事項
Purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
バッファー組成
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed : 2470098). In addition of this role of signal transduction in T-cell activation, CD3D plays an essential role in thymocyte differentiation. Indeed, participates in correct intracellular TCR-CD3 complex assembly and surface expression. In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly. Interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells (PubMed : 12215456).
See full target information CD3D
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Biochemistry and biophysics reports 40:101833 PubMed39398537

2024

CEACAM1 increased the lymphangiogenesis through miR-423-5p and NF- kB in Non-Small Cell Lung Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Yu,Wenke Cai,Tao Zhou,Bo Men,Shunqiong Chen,Dong Tu,Wei Guo,Jicui Wang,Feipeng Zhao,Yan Wang
View all publications
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Abcam product promise

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