Anti-Rb2 p130 抗体 [KAB40] (ab16673)
Key features and details
- Mouse monoclonal [KAB40] to Rb2 p130
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Rb2 p130 antibody [KAB40]
Rb2 p130 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [KAB40] to Rb2 p130 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Recombinant fragment corresponding to Human Rb2 p130 (N terminal).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
KAB40 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16673の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration.
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特記事項 |
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WB
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Two retinoblastoma related proteins, p107 and pRb2 / p130, which are structurally and functionally similar to the product of the retinoblastoma gene (pRb / p105), were cloned by taking advantage of their ability to bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain." Like pRb, both proteins play a fundamental role in growth control. These Rb family proteins were measured in a variety of lung neoplasms. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2 / p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer. -
細胞内局在
Nuclear -
参照データベース
- Entrez Gene: 5934 Human
- Entrez Gene: 19651 Mouse
- Entrez Gene: 81758 Rat
- Omim: 180203 Human
- SwissProt: Q08999 Human
- SwissProt: 235580 Mouse
- SwissProt: Q64700 Mouse
- SwissProt: O55081 Rat
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別名
- 130 kDa retinoblastoma associated protein antibody
- FLJ26459 antibody
- p130 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab16673 は論文での使用が確認できていません。