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AB197673

Anti-RAP1A 抗体

Anti-RAP1A antibody

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(4 Publications)

Rabbit Polyclonal RAP1A antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Fusion protein corresponding to RAP1A, fused to RAP1A.

別名を表示する

KREV1, RAP1A, Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling RAP1A with ab197673 at 1/35 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RAP1A antibody (AB197673)

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling RAP1A with ab197673 at 1/35 dilution.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

IHC-P

applications

免疫原

Fusion protein corresponding to RAP1A, fused to RAP1A. The exact immunogen used to generate this antibody is proprietary information.

P62834

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p>" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes (PubMed : 17916086). Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. Facilitates the progressive accumulation of CDH1 at mature desmosome junctions via cAMP-dependent signaling and its interaction with PKP3 (PubMed : 25208567). May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
See full target information RAP1A
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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

PloS one 20:e0328263 PubMed40680053

2025

Odontogenesis-associated phosphoprotein (ODAPH) Promotes Ameloblast adhesion and alkaline phosphatase (ALP) expression via LAMC2/ ITGB6/TGF-β1 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Mingyue Li,Jie Zhang,Shuang Xiao,Xinyang Liu,Shuai Song,Xiaoyuan Ye,Ruonan Bi,Yuguang Gao,Li Zhang

Laboratory investigation; a journal of technical methods and pathology 102:25-37 PubMed34725437

2021

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE mice atherosclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Lingbo Xu,Huiping Zhang,Yanhua Wang,Anning Yang,Xiaoyan Dong,Lingyu Gu,Dayue Liu,Ning Ding,Yideng Jiang

Frontiers in oncology 11:649980 PubMed34178637

2021

MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hailin Li,Guangyu Han,Xing Li,Bowen Li,Bo Wu,Hongyuan Jin,Lingli Wu,Wei Wang

Oncology reports 42:1815-1824 PubMed31545475

2019

Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qinfang Li,Aiping Xu,Yuan Chu,Tao Chen,Hongqi Li,Liqing Yao,Pinghong Zhou,Meidong Xu
View all publications
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