Anti-PU.1/Spi1 抗体 [PU1/2146] - BSA and Azide free
Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free
Be the first to review this product! Submit a review
|
(0 Publication)
Mouse Monoclonal PU.1/Spi1 antibody. Carrier free. Suitable for IHC-P, WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human SPI1 aa 1-200.
別名を表示する
Transcription factor PU.1, 31 kDa-transforming protein, SPI1
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
Formalin-fixed, paraffin-embedded human spleen tissue stained for PU.1/Spi1 using ab237905 at 2 μg/mL in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma tissue stained for PU.1/Spi1 using ab237905 at 2 μg/mL in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for PU.1/Spi1 using ab237905 at 2 μg/mL in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
Formalin-fixed, paraffin-embedded human lymph node tissue stained for PU.1/Spi1 using ab237905 at 2 μg/mL in immunohistochemical analysis.
- WB
Supplier Data
Western blot - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
All lanes:
Western blot - Anti-PU.1/Spi1 antibody [PU1/2146] (<a href='/products/primary-antibodies/pu1-spi1-antibody-pu1-2146-ab238054'>ab238054</a>) at 1 µg/mL
All lanes:
THP-1 (human monocytic leukemia cell line) whole cell lysate
Predicted band size: 31 kDa
false
- Protein Array
Unknown
Protein Array - Anti-PU.1/Spi1 antibody [PU1/2146] - BSA and Azide free (AB237905)
This data was produced with ab238054, the same antibody in a different formulation with BSA and Azide.
ab238054 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Reactivity data
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
PU.1 influences the development and function of various blood cells including macrophages neutrophils and B-cells. It is essential for the regulation of genes involved in immune responses cell proliferation and survival. PU.1 functions as part of a larger transcriptional regulatory complex and often partners with other transcription factors and coactivators to exert its effects. This cooperation allows precise gene expression control in specific cell lineages.
Pathways
Expression of PU.1 is critical in the hematopoietic development pathway and the immune response pathway. It closely interacts with other transcription factors like GATA-1 and C/EBPα forming a network that affects hematopoietic lineage commitment. Within these pathways PU.1 constantly coordinates signals that influence progenitor cell fate and differentiation ensuring a balanced proportion of cell types within the blood.
製品プロトコール
- Visit the General protocols
- Visit the Troubleshooting
ターゲットの情報
Abcam product promise
関連製品
Alternative Product
Primary Antibodies
AB88082
Anti-PU.1/Spi1 antibody [2G1]
primary-antibodies
pu1-spi1-antibody-2g1-ab88082
0
(0 reviews)
Alternative Product
Primary Antibodies
AB225040
Alexa Fluor® 647 Anti-PU.1/Spi1 antibody [EPR3158Y]
primary-antibodies
alexa-fluor-647-pu1-spi1-antibody-epr3158y-ab225040
0
(0 reviews)
Alternative Product
Primary Antibodies
AB76543
Anti-PU.1/Spi1 antibody [EPR3158Y]
primary-antibodies
pu1-spi1-antibody-epr3158y-ab76543
5
(3 reviews)
Alternative Product
Primary Antibodies
AB232383
Anti-PU.1/Spi1 antibody [EPR3158Y] - BSA and Azide free
primary-antibodies
pu1-spi1-antibody-epr3158y-bsa-and-azide-free-ab232383
0
(0 reviews)
Alternative Product
Primary Antibodies
AB183327
Anti-PU.1/Spi1 antibody [SP238]
primary-antibodies
pu1-spi1-antibody-sp238-ab183327
0
(0 reviews)
Alternative Version
Primary Antibodies
AB238054
Anti-PU.1/Spi1 antibody [PU1/2146]
primary-antibodies
pu1-spi1-antibody-pu1-2146-ab238054
0
(0 reviews)
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com