Anti-PTP4A3/PRL-R 抗体 (ab26947)
Key features and details
- Rabbit polyclonal to PTP4A3/PRL-R
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
製品の概要
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製品名
Anti-PTP4A3/PRL-R antibody
PTP4A3/PRL-R 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PTP4A3/PRL-R -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Recombinant full length protein corresponding to Human PTP4A3/PRL-R.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab26947の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/5000. Predicted molecular weight: 19 kDa.
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特記事項 |
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WB
1/5000. Predicted molecular weight: 19 kDa. |
ターゲット情報
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機能
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. -
組織特異性
Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. -
配列類似性
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain. -
翻訳後修飾
Farnesylated. Farnesylation is required for membrane targeting. -
細胞内局在
Cell membrane. Early endosome. - Information by UniProt
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別名
- Potentially prenylated protein tyrosine phosphatase antibody
- PRL 3 antibody
- PRL R antibody
see all
画像
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All lanes : Anti-PTP4A3/PRL-R antibody (ab26947) at 1/5000 dilution
Lane 1 : (T2.5) IPTG induction of the recombinant protein expression for 2.5 hours.
Lane 2 : (T0) before IPTG induction of the protein expression
Predicted band size: 19 kDa
Observed band size: 23.9 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (1)
ab26947 は 1 報の論文で使用されています。
- Laurent C et al. High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients. Cancer Res 71:666-74 (2011). WB ; Human . PubMed: 21135111