Anti-PSME1 抗体 (ab3333)
Key features and details
- Rabbit polyclonal to PSME1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-PSME1 antibody
PSME1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PSME1 -
由来種
Rabbit -
特異性
Detects PSME1 (proteasome activator complex subunit 1). -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Cow, Pig, Cynomolgus monkey
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免疫原
Synthetic peptide corresponding to Human PSME1 aa 5-22.
Sequence:RVQPEAQAKVDVFREDLC
(Peptide available asab4949) -
ポジティブ･コントロール
- Rat brain extract.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3333の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).
By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract. |
| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa). By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract. |
ターゲット情報
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機能
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. -
配列類似性
Belongs to the PA28 family. - Information by UniProt
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参照データベース
- Entrez Gene: 510041 Cow
- Entrez Gene: 102141082 Cynomolgus monkey
- Entrez Gene: 19186 Mouse
- Entrez Gene: 397572 Pig
- SwissProt: Q4U5R3 Cow
- SwissProt: P58238 Cynomolgus monkey
- SwissProt: P97371 Mouse
- SwissProt: Q64L94 Pig
see all -
別名
- 11S regulator complex alpha subunit antibody
- 11S regulator complex subunit alpha antibody
- 29 kD MCP activator subunit antibody
see all
画像
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Western blot - Anti-PSME1 antibody (ab3333)
Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.
データシートおよび資料
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Datasheet download
参考文献 (5)
ab3333 は 5 報の論文で使用されています。
- Koçberber Z et al. The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function. Front Endocrinol (Lausanne) 14:1176733 (2023). PubMed: 37201100
- Hülsemann M et al. TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia. Commun Biol 4:1091 (2021). PubMed: 34531530
- Donnelly SK et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol 216:4331-4349 (2017). PubMed: 29061650
- Glogauer JE et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). PubMed: 26112922
- Pla A et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . PubMed: 24556681
