AB172628

Anti-PSD95 (phospho T19) 抗体 [EPR2619(2)]

Name: Anti-PSD95 (phospho T19) 抗体 [EPR2619(2)] (ab172628) | Abcam
Brand: Abcam Limited
SKU: AB172628
Price: 31000 JPY
Availability: InStock
Rating: 5 (1 reviews)

Anti-PSD95 (phospho T19) antibody [EPR2619(2)]

20ul selling size
RabMAb
Recombinant
詳細を見る

(1 Review)

(5 Publications)

Rabbit Recombinant Monoclonal PSD95 phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

別名を表示する

PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90

1 Images

Supplier Data

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)

All lanes:

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628) at 1/1000 dilution

Lane 1:

Fetal brain lysate, untreated at 10 µg

Lane 2:

Fetal brain lysate, treated with Lambda Phosphatase at 10 µg

Predicted band size: 80 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR2619(2)

アイソタイプ

IgG

キャリアフリー

交差種

Human

アプリケーション

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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製品の詳細

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

出荷温度

Conditional Ambient

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (PubMed : 26334723).

See full target information DLG4 pT19

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文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Brain research bulletin 165:272-280 PubMed33075417

2020

Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hasan Alhaddad,Fawaz Alasmari,Balsam Alhamadani,Woonyen Wong,Richard L Bell,Youssef Sari

Frontiers in cellular neuroscience 13:447 PubMed31749684

2019

Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Mice Contributes to Synaptic and Social Deficiency.

Applications

Unspecified application

Species

Unspecified reactive species

Mengmeng Wang,Xinyan Liu,Yilin Hou,Haifeng Zhang,Junjun Kang,Fei Wang,Youyi Zhao,Jing Chen,Xufeng Liu,Yazhou Wang,Shengxi Wu

The EMBO journal 37:122-138 PubMed29118000

2017

Ca/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down.

Applications

Unspecified application

Species

Unspecified reactive species

Dhrubajyoti Chowdhury,Matthew Turner,Tommaso Patriarchi,Anne C Hergarden,David Anderson,Yonghong Zhang,Junqing Sun,Chao-Yin Chen,James B Ames,Johannes W Hell

Frontiers in molecular neuroscience 10:295 PubMed28979184

2017

SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.

Applications

Unspecified application

Species

Unspecified reactive species

Dae Hwan Kim,Minkyung Kang,Chong-Hyun Kim,Yun Hyun Huh,In Ha Cho,Hyun-Hee Ryu,Kyung Hwun Chung,Chul-Seung Park,Sangmyung Rhee,Yong-Seok Lee,Woo Keun Song

Bipolar disorders 18:473-480 PubMed27687706

2016

Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Eléonore Beurel,Steven F Grieco,Celeste Amadei,Kimberlee Downey,Richard S Jope

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PSD95 (phospho T19) 抗体 [EPR2619(2)]

Anti-PSD95 (phospho T19) antibody [EPR2619(2)]

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)

関連する標識済み抗体及び組成の異なる製品 (1)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (5)

Abcam product promise