AB2930

Anti-PSD93 抗体

Name: Anti-PSD93 抗体 (ab2930) | Abcam
Brand: Abcam Limited
SKU: AB2930
Price: 81000 JPY
Availability: InStock

Anti-PSD93 antibody

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(7 Publications)

Rabbit Polyclonal PSD93 antibody. Suitable for IHC-Fr, WB, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus.

別名を表示する

Dlgh2, Dlg2, Disks large homolog 2, Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Chapsyn-110

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF image of ab2930 stained PC12 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab2930, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

IHC-Fr

Supplier Data

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

Immunolocalization of PSD-93 in rat cerebellum using ab2930.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

交差種

Mouse, Rat, Human

アプリケーション

WB, ICC/IF, IHC-Fr

applications

免疫原

Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q63622

特異性

Detects Post Synaptic Density 93 (PSD 93) from rat tissues. This antibody does not detect other synapse-associated protein family members.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCFr-species-checked": "testedAndGuaranteed", "IHCFr-species-dilution-info": "5 µg/mL", "IHCFr-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

バッファー組成

Preservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

See full target information Dlg2

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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

Cells 12: PubMed36980245

2023

JNK Activation Correlates with Cognitive Impairment and Alteration of the Post-Synaptic Element in the 5xFAD AD Mouse Model.

Applications

Unspecified application

Species

Unspecified reactive species

Erica Cecilia Priori,Clara Alice Musi,Arianna Giani,Luca Colnaghi,Ivana Milic,Andrew Devitt,Tiziana Borsello,Mariaelena Repici

BMC biology 19:256 PubMed34911542

2021

JNK signaling provides a novel therapeutic target for Rett syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Clara Alice Musi,Anna Maria Castaldo,Anna Elisa Valsecchi,Sara Cimini,Noemi Morello,Riccardo Pizzo,Alessandra Renieri,Ilaria Meloni,Maurizio Bonati,Maurizio Giustetto,Tiziana Borsello

Cancer biology & therapy 20:897-911 PubMed30862230

2019

MicroRNA-23a depletion promotes apoptosis of ovarian cancer stem cell and inhibits cell migration by targeting DLG2.

Applications

Unspecified application

Species

Unspecified reactive species

Ru-Jin Zhuang,Xiao-Xu Bai,Wei Liu

Journal of Alzheimer's disease : JAD 63:1141-1159 PubMed29710724

2018

Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.

Applications

Unspecified application

Species

Unspecified reactive species

Yacoubou Abdoul Razak Mahaman,Fang Huang,Mengjuan Wu,Yuman Wang,Zhen Wei,Jian Bao,Maibouge Tanko Mahamane Salissou,Dan Ke,Qun Wang,Rong Liu,Jian-Zhi Wang,Bin Zhang,Dan Chen,Xiaochuan Wang

Cell death & disease 4:e673 PubMed23764854

2013

Glycation exacerbates the neuronal toxicity of β-amyloid.

Applications

Unspecified application

Species

Mouse

X-H Li,L-L Du,X-S Cheng,X Jiang,Y Zhang,B-L Lv,R Liu,J-Z Wang,X-W Zhou

The Journal of neuroscience : the official journal of the Society for Neuroscience 31:6800-8 PubMed21543610

2011

PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.

Applications

ICC/IF

Species

Rat

Qian Sun,Gina G Turrigiano

Journal of Cancer 1:14-22 PubMed20842219

2010

Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26.

Applications

Species

Human

Ziad J Sahab,Michael D Hall,Lihua Zhang,Amrita K Cheema,Stephen W Byers

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PSD93 抗体

Anti-PSD93 antibody

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

特異性

代替製品

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (7)

Abcam product promise