Anti-Protein Tax-1 抗体 [1A3] (ab26997)
Key features and details
- Mouse monoclonal [1A3] to Protein Tax-1
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Human T-cell leukemia virus type I
- Isotype: IgG2a
製品の概要
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製品名
Anti-Protein Tax-1 antibody [1A3] -
製品の詳細
Mouse monoclonal [1A3] to Protein Tax-1 -
由来種
Mouse -
アプリケーション
適用あり: ICC/IF, IHC-P, WBmore details -
種交差性
交差種: Human T-cell leukemia virus type I -
免疫原
Recombinant full length protein corresponding to Protein Tax-1.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Constituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
1A3 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab26997の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
1/50 - 1/1000.
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| IHC-P |
1/50 - 1/800.
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| WB |
1/50 - 1/500.
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| 特記事項 |
|---|
|
ICC/IF
1/50 - 1/1000. |
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IHC-P
1/50 - 1/800. |
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WB
1/50 - 1/500. |
ターゲット情報
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関連性
The Tax protein of HTLV1 is an autoregulator of enhanced viral RNA transcription and it trans activates the viral 21 bp enhancer. -
別名
- HTLV1 p40 antibody
- HTLV1 Tax antibody
- p40 antibody
- tax antibody
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab26997 は 5 報の論文で使用されています。
- Fernandez MV et al. Elucidating the Basis for Permissivity of the MT-4 T-Cell Line to Replication of an HIV-1 Mutant Lacking the gp41 Cytoplasmic Tail. J Virol 94:N/A (2020). PubMed: 32938764
- Cheng W et al. Activation of Notch1 signaling by HTLV-1 Tax promotes proliferation of adult T-cell leukemia cells. Biochem Biophys Res Commun 512:598-603 (2019). PubMed: 30914196
- Fernandez MV et al. Authentication Analysis of MT-4 Cells Distributed by the National Institutes of Health AIDS Reagent Program. J Virol 93:N/A (2019). PubMed: 31554688
- Zimmerman B et al. Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma. Leuk Res 35:1491-7 (2011). WB . PubMed: 21802726
- Watters KM et al. Cytokine and growth factor expression by HTLV-1 Lck-tax transgenic cells in SCID mice. AIDS Res Hum Retroviruses 26:593-603 (2010). WB . PubMed: 20438380