Anti-Prominin 2 抗体 (ab118492)
Key features and details
- Rabbit polyclonal to Prominin 2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Prominin 2 antibody
Prominin 2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Prominin 2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids of Human Prominin 2 (NP_653308.2).
-
ポジティブ･コントロール
- Human Lung (Respiratory Epithelium) and Uterus tissues.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab118492の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 15 - 20 µg/ml.
|
| 特記事項 |
|---|
|
IHC-P
Use a concentration of 15 - 20 µg/ml. |
ターゲット情報
-
組織特異性
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines. -
配列類似性
Belongs to the prominin family. -
翻訳後修飾
Glycosylated. -
細胞内局在
Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane. Cell projection > cilium membrane. Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells. - Information by UniProt
-
参照データベース
- Entrez Gene: 150696 Human
- SwissProt: Q8N271 Human
- Unigene: 469313 Human
-
別名
- hPROML2 antibody
- MGC138714 antibody
- OTTHUMP00000160939 antibody
see all
画像
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prominin 2 antibody (ab118492)ab118492 at 0.5 µg/ml staining Prominin 2 in Human Lung, Respiratory Epithelium by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prominin 2 antibody (ab118492)ab118492 at 0.5 µg/ml staining Prominin 2 in Human Uterus by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab118492 は 2 報の論文で使用されています。
- Tang J et al. Prominin 2 decreases cisplatin sensitivity in non-small cell lung cancer and is modulated by CTCC binding factor. Radiol Oncol 57:325-336 (2023). PubMed: 37665741
- Pereira MF et al. Effects of the oestrogen receptor antagonist Fulvestrant on expression of genes that affect organization of the epididymal epithelium. Andrology 2:559-71 (2014). PubMed: 24782439