Anti-Progesterone 抗体 [11P14] (ab20236)
Key features and details
- Mouse monoclonal [11P14] to Progesterone
- Suitable for: RIA
- Reacts with: Human
- Isotype: IgG2b
製品の概要
-
製品名
Anti-Progesterone antibody [11P14]
Progesterone 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [11P14] to Progesterone -
由来種
Mouse -
アプリケーション
適用あり: RIAmore details -
種交差性
交差種: Human -
免疫原
11a-Hydroxyprogesterone conjugated to bovine serum albumin.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
-
精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
11P14 -
ミエローマ
P3-NS1/1-Ag4-1 -
アイソタイプ
IgG2b -
軽鎖の種類
unknown -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20236の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
RIA |
Use at an assay dependent concentration.
|
特記事項 |
---|
RIA
Use at an assay dependent concentration. |
ターゲット情報
-
関連性
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap. It is composed of three domains: a modulating N terminal domain, a DNA binding domain and a C terminal steroid binding domain. Progesterone levels 1. men 30-60 pg/0.1ml 2. women pre ovulatory phase: 20-160 pg/0.1ml; ovulatory phase: 1,000-1,700 pg/0.1ml; post ovulatory phase: 1,000-1,700 pg/0.1ml; Pregnant: 16-18 weeks: 300-800 pg/0.1ml; 28-30 weeks: 6,500-14,700 pg/0.1ml; 38-40 weeks: 12,000-19,000 pg/0.1ml. -
細胞内局在
Secreted -
別名
- Pregn 4 ene 3 20 dione antibody
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab20236 は 1 報の論文で使用されています。
- Fantl VE et al. The production of high affinity monoclonal antibodies to progesterone. J Steroid Biochem 17:125-30 (1982). PubMed: 7109599