Anti-PRL-1 抗体 (ab168643)
Key features and details
- Mouse polyclonal to PRL-1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PRL-1 antibody
PRL-1 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to PRL-1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cynomolgus monkey, Orangutan
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免疫原
Recombinant full length protein within Human PRL-1 aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. NP_003454.1
Database link: Q93096 -
ポジティブ･コントロール
- PRL-1transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.4
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab168643の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa. |
ターゲット情報
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機能
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. -
組織特異性
Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines. -
配列類似性
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain. -
発生段階
Expressed in fetal liver. -
翻訳後修飾
Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus. -
細胞内局在
Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm > cytoskeleton > spindle. And mitotic spindle. - Information by UniProt
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参照データベース
- Entrez Gene: 7803 Human
- Entrez Gene: 100044742 Mouse
- Entrez Gene: 19243 Mouse
- Omim: 601585 Human
- SwissProt: Q93096 Human
- SwissProt: Q63739 Mouse
- Unigene: 227777 Human
- Unigene: 480653 Mouse
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別名
- HH 72 antibody
- HH72 antibody
- Hypothetical protein DKFZp779M0721 antibody
see all
画像
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Western blot - Anti-PRL-1 antibody (ab168643)All lanes : Anti-PRL-1 antibody (ab168643) at 1 µg/ml
Lane 1 : PRL-1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 20 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab168643 は 1 報の論文で使用されています。
- Shirasaki T et al. Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET. Nat Commun 13:3176 (2022). PubMed: 35676290
