Anti-Prealbumin 抗体 [CPTC-TTR-1]
Anti-Prealbumin antibody [CPTC-TTR-1]
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(1 Publication)
Mouse Monoclonal Prealbumin antibody. Suitable for WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TTR.
別名を表示する
PALB, TTR, Transthyretin, ATTR, Prealbumin, TBPA
- Protein Array
Unknown
Protein Array - Anti-Prealbumin antibody [CPTC-TTR-1] (AB268123)
Protein Array containing more than 19,000 full-length human proteins using ab268123.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
- WB
Unknown
Western blot - Anti-Prealbumin antibody [CPTC-TTR-1] (AB268123)
All lanes:
Western blot - Anti-Prealbumin antibody [CPTC-TTR-1] (ab268123) at 2 µg/mL
All lanes:
Human kidney tissue lysate
Predicted band size: 15 kDa
false
Reactivity data
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Prealbumin interacts with retinol-binding protein to form a complex essential for vitamin A transportation. This complex prevents renal filtration of retinol-binding protein thereby conserving vitamin A in circulation. The protein's role extends beyond transport as it influences neurophysiological processes due to its ability to bind thyroid hormones and affect gene expression related to metabolism. Prealbumin is primarily a part of the thyroxine-transferring complex reinforcing its critical position in hormonal and vitamin dynamics.
Pathways
Prealbumin's role in the thyroxine-binding globulin pathway highlights its importance in the endocrine system. Another pathway where prealbumin contributes significantly is the vitamin A metabolic pathway. In these pathways prealbumin maintains functional relationships with proteins like retinol-binding protein and thyroxine-binding globulin which jointly modulate thyroid hormone transport and vitamin A dynamics across cellular membranes.
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ターゲットの情報
文献 (1)
Recent publications for all applications. Explore the full list and refine your search
BMC nephrology 25:387 PubMed39478440
2024
Applications
Unspecified application
Species
Unspecified reactive species
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