Anti-PNRC2 抗体 (ab235599)
Key features and details
- Rabbit polyclonal to PNRC2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PNRC2 antibody -
製品の詳細
Rabbit polyclonal to PNRC2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Cow
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免疫原
Recombinant full length protein corresponding to Human PNRC2 aa 1 to the C-terminus.
Database link: Q9NPJ4-1 -
ポジティブ･コントロール
- WB: U-251 MG whole cell lysate. IHC-P: Human kidney tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Purity >95% -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab235599の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/20 - 1/200.
|
|
| WB |
1/500 - 1/2000.
|
| 特記事項 |
|---|
|
IHC-P
1/20 - 1/200. |
|
WB
1/500 - 1/2000. |
ターゲット情報
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機能
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure. -
組織特異性
Expressed in heart, lung, muscle and brain. -
配列類似性
Belongs to the PNRC family. PNRC2 subfamily. -
ドメイン
The interaction between PNRC2 and nuclear receptors is dependent on the SH3 binding motif. -
細胞内局在
Nucleus. Cytoplasm > P-body. - Information by UniProt
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参照データベース
- Entrez Gene: 767836 Cow
- Entrez Gene: 100505603 Human
- Entrez Gene: 55629 Human
- Omim: 611882 Human
- SwissProt: Q0VCW6 Cow
- SwissProt: Q9NPJ4 Human
- Unigene: 512636 Human
- Unigene: 644217 Human
see all -
別名
- 0610011E17Rik antibody
- D4Bwg0593e antibody
- FLJ20312 antibody
see all
画像
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Western blot - Anti-PNRC2 antibody (ab235599)Anti-PNRC2 antibody (ab235599) at 1/500 dilution + U-251 MG (human brain glioma cell line) whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PNRC2 antibody (ab235599)Paraffin-embedded human kidney tissue stained for PNRC2 using ab235599 at 1/100 dilution in immunohistochemical analysis.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab235599 は論文での使用が確認できていません。