Anti-PLXNA3 抗体 (ab41564)
Key features and details
- Rabbit polyclonal to PLXNA3
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-PLXNA3 antibody -
製品の詳細
Rabbit polyclonal to PLXNA3 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Human
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免疫原
Synthetic peptide corresponding to Mouse PLXNA3 aa 1100-1200.
(Peptide available asab41563) -
ポジティブ･コントロール
- This antibody gave a positive signal in P0 mouse brain and mouse hippocampus tissue lysates
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab41564の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
Use a concentration of 1 µg/ml. Detects a band of approximately 207 kDa (predicted molecular weight: 207 kDa).
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 207 kDa (predicted molecular weight: 207 kDa). |
ターゲット情報
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関連性
Plexin A3 is a coreceptor for the class 3 secreted semaphorins. This family of semaphorins binds to a complex composed of a neuropilin and a plexin. The plexin type modulates the affinity of the complex for specific semaphorins and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Plexin A3 is a putative receptor involved in the development of neural and epithelial tissues. -
細胞内局在
Membrane; single-pass type I membrane protein. -
参照データベース
- Entrez Gene: 55558 Human
- Entrez Gene: 18846 Mouse
- Omim: 300022 Human
- SwissProt: P51805 Human
- SwissProt: P70208 Mouse
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別名
- HSSEXGENE antibody
- Plexin 4 antibody
- Plexin A3 antibody
see all
画像
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Western blot - Anti-PLXNA3 antibody (ab41564)All lanes : Anti-PLXNA3 antibody (ab41564) at 1 µg/ml
Lane 1 : P0 Mouse Brain Mouse Tissue Lysate
Lane 2 : Hippocampus (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 207 kDa
Observed band size: 207 kDa
Additional bands at: 32 kDa, 50 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab41564 は 4 報の論文で使用されています。
- Szczurkowska J et al. Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development. Cell Rep 38:110483 (2022). PubMed: 35294878
- Mohan V et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci 39:6233-6250 (2019). PubMed: 31182634
- Demyanenko GP et al. Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling. J Neurosci 34:11274-87 (2014). IHC-FoFr ; Mouse . PubMed: 25143608
- Staton CA et al. Expression of class 3 semaphorins and their receptors in human breast neoplasia. Histopathology 59:274-82 (2011). PubMed: 21884206