AB230250
Anti-PLA2G4C 抗体
Anti-PLA2G4C antibody
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(1 Publication)
Rabbit Polyclonal PLA2G4C antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human PLA2G4C aa 1-200.
別名を表示する
Cytosolic phospholipase A2 gamma, cPLA2-gamma, Cytosolic lysophospholipase, Cytosolic lysophospholipid O-acyltransferase, Phospholipase A2 group IVC, PLA2G4C
2 Images
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLA2G4C antibody (AB230250)
Paraffin-embedded human skeletal muscle tissue stained for PLA2G4C with ab230250 at 1/100 dilution in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLA2G4C antibody (AB230250)
Paraffin-embedded human heart tissue stained for PLA2G4C with ab230250 at 1/100 dilution in immunohistochemical analysis.
代替製品
組合せ製品
![Flow Cytometry (Intracellular) - Anti-sPLA2-X antibody [EPR11202] (AB166634)](https://content.abcam.com/products/images/spla2-x-antibody-epr11202-ab166634--flow-cytometry-intracellular-img28696.jpg)
Reactivity data
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
出荷温度及び保存条件
製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
製品プロトコール
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
ターゲットの情報
Calcium-independent phospholipase, lysophospholipase and O-acyltransferase involved in phospholipid remodeling with implications in endoplasmic reticulum membrane homeostasis and lipid droplet biogenesis (PubMed : 10085124, PubMed : 10358058, PubMed : 19501189, PubMed : 28336330, PubMed : 9705332). Preferentially hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids with choline and ethanolamine head groups, producing lysophospholipids that are used in deacylation-reacylation cycles (PubMed : 10085124, PubMed : 10358058, PubMed : 19501189, PubMed : 28336330, PubMed : 9705332). Transfers the sn-1 fatty acyl from one lysophospholipid molecule to the sn-2 position of another lysophospholipid to form diacyl, alkylacyl and alkenylacyl glycerophospholipids. Cleaves ester bonds but not alkyl or alkenyl ether bonds at sn-1 position of lysophospholipids (PubMed : 15944408, PubMed : 19501189). Catalyzes sn-2 fatty acyl transfer from phospholipids to the sn-2 position of 1-O-alkyl or 1-O-alkenyl lysophospholipids with lower efficiency (PubMed : 15944408, PubMed : 19501189). In response to dietary fatty acids, may play a role in the formation of nascent lipid droplets from the endoplasmic reticulum likely by regulating the phospholipid composition of these organelles (PubMed : 28336330).. (Microbial infection) May play a role in replication and assembly of human hepatitis C virus (HCV) (PubMed : 23015700, PubMed : 28336330). In response to HCV infection, promotes remodeling of host endoplasmic reticulum membranes to form organelle-like structures called membranous web, where HCV replication occur (PubMed : 23015700). Can further mediate translocation of replication complexes to lipid droplets to enable virion assembly (PubMed : 23015700, PubMed : 28336330).. (Microbial infection) May facilitate human T-lymphotropic virus type 1 (HTLV-1) infection by promoting leukotriene B4 (LTB4) biosynthesis. LTB4 acts as a chemoattractant for HTLV-1-infected CD4-positive T cells and favors cell to cell viral transmission.
文献 (1)
Recent publications for all applications. Explore the full list and refine your search
iScience 26:105745 PubMed36590171
2023
Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4.
Applications
Unspecified application
Species
Unspecified reactive species
Chenggang Zhang,Xianxiong Ma,Guanxin Wei,Xiuxian Zhu,Peng Hu,Xiang Chen,Dianshi Wang,Yuan Li,Tuo Ruan,Weikang Zhang,Kaixiong Tao,Chuanqing Wu
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