Anti-PGC1 beta 抗体 (ab118603)
Key features and details
- Goat polyclonal to PGC1 beta
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PGC1 beta antibody
PGC1 beta 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to PGC1 beta -
由来種
Goat -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Rhesus monkey, Common marmoset
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免疫原
Synthetic peptide: AGNDCGALLDEELS, corresponding to amino acids 2-15 of Human PGC1 beta (NP_573570.3).
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ポジティブ･コントロール
- Human Heart, Human Spleen
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特記事項
This product may be covered by one or more of the following U.S. Patents.
6,166,192
6,426,411
6,525,178
6,872,391
6,908,987
7,250,283
7,091,006
7,354,738
8,105,774
8,445,233The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Co-activators/co-repressors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab118603の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 3.75 - 7.5 µg/ml.
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| 特記事項 |
|---|
|
IHC-P
Use a concentration of 3.75 - 7.5 µg/ml. |
ターゲット情報
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機能
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. -
組織特異性
Ubiquitous with higher expression in heart, brain and skeletal muscle. -
配列類似性
Contains 1 RRM (RNA recognition motif) domain. -
ドメイン
Contains 2 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which are usually required for the association with nuclear receptors. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 133522 Human
- Entrez Gene: 170826 Mouse
- Entrez Gene: 291567 Rat
- Omim: 608886 Human
- SwissProt: Q86YN6 Human
- SwissProt: Q8VHJ7 Mouse
- SwissProt: Q811R2 Rat
- Unigene: 483816 Human
see all -
別名
- PERC antibody
- peroxisome proliferative activated receptor, gamma, coactivator 1, antibody
- peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab118603 は論文での使用が確認できていません。