JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB210265

PerCP/Cy5.5® Anti-CD4 抗体 [GK1.5]

PerCP/Cy5.5® Anti-CD4 antibody [GK1.5]

Be the first to review this product! Submit a review

|

(2 Publications)

Anti-CD4 antibody [GK1.5] conjugated to PerCP/Cy5.5® - suitable for flow cytometry, and reacts with mouse samples. Clone [GK1.5] is a rat monoclonal antibody and one of the most commonly used clones for flow cytometry.

Design your panel with our interactive flow cytometry panel builder. Click here.

別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, Cd4

1 Images
Flow Cytometry - PerCP/Cy5.5® Anti-CD4 antibody [GK1.5] (AB210265)
  • Flow Cyt

Supplier Data

Flow Cytometry - PerCP/Cy5.5® Anti-CD4 antibody [GK1.5] (AB210265)

Flow cytometric analysis of C57Bl/6 splenocytes labeling CD4 with 0.06 μg ab210265 (solid line), compared with 0.06 μg Per-Cy5.5 Rat IgG2b isotype control (dashed line).

関連する標識済み抗体及び組成の異なる製品 (6)

  • 660 APC

    APC Anti-CD4 antibody [GK1.5]

  • 519 FITC

    FITC Anti-CD4 antibody [GK1.5]

  • 519 FITC

    FITC Anti-CD4 antibody [GK1.5]

  • 667 PE/Cy5®

    PE/Cy5® Anti-CD4 antibody [GK1.5]

  • 704 redFluor™ 710

    redFluor™ 710 Anti-CD4 antibody [GK1.5]

  • 450 violetFluor™ 450

    violetFluor™ 450 Anti-CD4 antibody [GK1.5]

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

GK1.5

アイソタイプ

IgG2b

軽鎖のタイプ

kappa

標識

PerCP/Cy5.5®

励起波長/蛍光波長

Ex: 482nm, Em: 695nm

キャリアフリー

No

交差種

Mouse

アプリケーション

Flow Cyt

applications

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 0.06 μg.</p>" }, "Syrian hamster": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
精製に関する特記事項
ab210265 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
バッファー組成
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
See full target information Cd4

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Environmental toxicology 38:146-158 PubMed36181686

2022

Blimp1 suppressed CD4 T cells-induced activation of fibroblast-like synoviocytes by upregulating IL-10 via the rho pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qingliang Meng,Zhike Wen,Wanting Meng,Hua Bian,Huimin Gu,Ruiting Zuo,Junping Zhan,Huilian Wang,Xiyun Miao,Wei Fan,Zipeng Zhou,Fuzeng Zheng,Liying Wang,Xiao Su,Junfu Ma

Nature cancer 3:337-354 PubMed35256819

2022

An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah Chan,Nicole Belmar,Sun Ho,Bryan Rogers,Marcia Stickler,Michelle Graham,Eileen Lee,Ninian Tran,Dong Zhang,Priyanka Gupta,Mien Sho,Tracy MacDonough,Andrew Woolley,Han Kim,Hong Zhang,Wei Liu,Pingping Zheng,Zoltan Dezso,Kyle Halliwill,Michele Ceccarelli,Susan Rhodes,Archana Thakur,Charles M Forsyth,Mengli Xiong,Siu Sze Tan,Ramesh Iyer,Marc Lake,Enrico Digiammarino,Li Zhou,Lance Bigelow,Kenton Longenecker,Russell A Judge,Cassie Liu,Max Trumble,Jonathan P Remis,Melvin Fox,Belinda Cairns,Yoshiko Akamatsu,Diane Hollenbaugh,Fiona Harding,Hamsell M Alvarez
View all publications

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com