PerCP Anti-CD4 抗体 [MEM-241] (ab65951)
Key features and details
- PerCP Mouse monoclonal [MEM-241] to CD4
- Suitable for: Flow Cyt
- Reacts with: Human, Cynomolgus monkey
- Conjugation: PerCP. Ex: 482nm, Em: 675nm
- Isotype: IgG1
製品の概要
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製品名
PerCP Anti-CD4 antibody [MEM-241]
CD4 一次抗体 製品一覧 -
製品の詳細
PerCP Mouse monoclonal [MEM-241] to CD4 -
由来種
Mouse -
標識
PerCP. Ex: 482nm, Em: 675nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human, Cynomolgus monkey -
免疫原
Recombinant fragment (Fc-tag) corresponding to Human CD4 (N terminal).
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特記事項
The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading... -
精製度
Size exclusion -
特記事項（精製）
purity >95% by SDS-PAGE. -
ポリ/モノ
モノクローナル -
クローン名
MEM-241 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
- APC Anti-CD4 antibody [MEM-241] (ab18280)
- FITC Anti-CD4 antibody [MEM-241] (ab18281)
- PE Anti-CD4 antibody [MEM-241] (ab18282)
- APC/Cy7® Anti-CD4 antibody [MEM241] (ab233298)
- PE/Cy7® Anti-CD4 antibody [MEM241] (ab233660)
- Alexa Fluor® 700 Anti-CD4 antibody [MEM-241] (ab270671)
- Biotin Anti-CD4 antibody [MEM-241] (ab28069)
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65951の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | (4) |
Use at an assay dependent concentration.
ab118658 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab118658 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. -
配列類似性
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻訳後修飾
Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts. -
細胞内局在
Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum. - Information by UniProt
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参照データベース
- Entrez Gene: 101864991 Cynomolgus monkey
- Entrez Gene: 920 Human
- Omim: 186940 Human
- SwissProt: P79185 Cynomolgus monkey
- SwissProt: P01730 Human
- Unigene: 631659 Human
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別名
- CD 4 antibody
- CD4 (L3T4) antibody
- CD4 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab65951 は 3 報の論文で使用されています。
- Chua KV et al. Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial-Mesenchymal Transition-Promoted M2-Macrophages, HSP90a Secretion, and Tumor Growth. Cells 9:N/A (2019). PubMed: 31905895
- Xue L et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol 133:1184-94 (2014). Flow Cyt ; Human . PubMed: 24388011
- Bastien JP et al. Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease. Blood 116:4859-69 (2010). Flow Cyt ; Human . PubMed: 20798236