JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB65951

PerCP Anti-CD4 抗体 [MEM-241]

PerCP Anti-CD4 antibody [MEM-241]

3

(4 Reviews)

|

(3 Publications)

Anti-CD4 antibody [MEM-241] conjugated to PerCP - suitable for flow cytometry, and reacts with human and Crab-Eating Macaque samples. Clone [MEM-241] is a mouse monoclonal antibody cited in 8 publications.

Design your panel with our interactive flow cytometry panel builder. Click here.

別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

2 Images
Flow Cytometry - PerCP Anti-CD4 antibody [MEM-241] (AB65951)
  • Flow Cyt

Supplier Data

Flow Cytometry - PerCP Anti-CD4 antibody [MEM-241] (AB65951)

Separation of human CD4 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD4 (MEM-241) PerCP antibody (concentration in sample 0.33 µg/ml).

Flow Cytometry - PerCP Anti-CD4 antibody [MEM-241] (AB65951)
  • Flow Cyt

Supplier Data

Flow Cytometry - PerCP Anti-CD4 antibody [MEM-241] (AB65951)

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD4 (MEM-241) PerCP antibody (concentration in sample 0.33 µg/ml).

関連する標識済み抗体及び組成の異なる製品 (7)

  • 660 APC

    APC Anti-CD4 antibody [MEM-241]

  • 785 APC/Cy7®

    APC/Cy7® Anti-CD4 antibody [MEM-241]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD4 antibody [MEM-241]

  • Biotin

    Biotin Anti-CD4 antibody [MEM-241]

  • 519 FITC

    FITC Anti-CD4 antibody [MEM-241]

  • 578 PE

    PE Anti-CD4 antibody [MEM-241]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD4 antibody [MEM-241]

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

MEM-241

アイソタイプ

IgG1

軽鎖のタイプ

kappa

標識

PerCP

励起波長/蛍光波長

Ex: 490nm, Em: 675nm

キャリアフリー

No

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/percp-mouse-igg1-kappa-monoclonal-b11-6-isotype-control-ab118658'>ab118658</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

製品の詳細

The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Size-exclusion chromatography
精製に関する特記事項
purity >95% by SDS-PAGE.
バッファー組成
Preservative: 0.097% Sodium azide Constituents: PBS, 0.2% BSA
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Cells 9: PubMed31905895

2019

Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial-Mesenchymal Transition-Promoted M2-Macrophages, HSP90α Secretion, and Tumor Growth.

Applications

Unspecified application

Species

Unspecified reactive species

Kee Voon Chua,Chi-Shuan Fan,Chia-Chi Chen,Li-Li Chen,Shu-Chen Hsieh,Tze-Sing Huang

The Journal of allergy and clinical immunology 133:1184-94 PubMed24388011

2014

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.

Applications

Flow Cyt

Species

Human

Luzheng Xue,Maryam Salimi,Isabel Panse,Jenny M Mjösberg,Andrew N J McKenzie,Hergen Spits,Paul Klenerman,Graham Ogg

Blood 116:4859-69 PubMed20798236

2010

Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease.

Applications

Flow Cyt

Species

Human

Jean-Philippe Bastien,Gorazd Krosl,Cynthia Therien,Marissa Rashkovan,Christian Scotto,Sandra Cohen,David S Allan,Donna Hogge,R Maarten Egeler,Claude Perreault,Denis Claude Roy
View all publications

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com