PE Anti-TLR6 抗体 [TLR6.127] (ab171564)
Key features and details
- PE Mouse monoclonal [TLR6.127] to TLR6
- Suitable for: IP, ICC/IF, Flow Cyt, Functional Studies
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
製品の概要
-
製品名
PE Anti-TLR6 antibody [TLR6.127]
TLR6 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [TLR6.127] to TLR6 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: IP, ICC/IF, Flow Cyt, Functional Studiesmore details -
種交差性
交差種: Human -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
TLR6.127 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab171564の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| ICC/IF |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
Use at an assay dependent concentration.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
| Functional Studies |
Use at an assay dependent concentration.
For neutralization of biological activity, in vitro dilutions have to be made according to the amounts of TLR6 to be inactivated. |
| 特記事項 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
Flow Cyt
Use at an assay dependent concentration. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
Functional Studies
Use at an assay dependent concentration. For neutralization of biological activity, in vitro dilutions have to be made according to the amounts of TLR6 to be inactivated. |
ターゲット情報
-
機能
Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. -
組織特異性
Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. -
配列類似性
Belongs to the Toll-like receptor family.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
細胞内局在
Cell membrane. Cytoplasmic vesicle > phagosome membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 10333 Human
- Omim: 605403 Human
- SwissProt: Q9Y2C9 Human
- Unigene: 575090 Human
-
別名
- CD286 antibody
- CD286 antigen antibody
- TLR 6 antibody
see all
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab171564 は論文での使用が確認できていません。
