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AB322455

PE Anti-Sialoadhesin/CD169 抗体 [EPR27102-11]

PE Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

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Rabbit Recombinant Monoclonal Sialoadhesin/CD169 antibody - conjugated to PE. Suitable for Flow Cyt, ICC/IF, IHC-P and reacts with Mouse, Rat samples.

別名を表示する

CD169, Sa, Sn, Siglec1, Sialoadhesin, Sheep erythrocyte receptor, Sialic acid-binding Ig-like lectin 1, SER, Siglec-1

2 Images
Flow Cytometry - PE Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (AB322455)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (AB322455)

Flow cytometric analysis of Mouse bone marrow cells cells labelling Sialoadhesin/CD169 with ab322455 at 1/5000 dilution (0.01ug) / Right compared with a Rabbit IgG monoclonal [EPR25A] - Isotype Control (Phycoerythrin) (ab209478) / Left isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody).

Mouse bone marrow cells are co-stained with F4/80 conjugated Alexa Fluor®647.
Gated on viable cell.

Flow Cytometry - PE Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (AB322455)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-Sialoadhesin/CD169 antibody [EPR27102-11] (AB322455)

Flow cytometric analysis of Mouse bone marrow cells cells labelling Sialoadhesin/CD169 with ab322455 at 1/5000 dilution (0.01ug) / Right compared with a Rabbit IgG monoclonal [EPR25A] - Isotype Control (Phycoerythrin) (ab209478) / Left isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody).

Mouse bone marrow cells are co-stained with CD3 conjugated Alexa Fluor®647.
Gated on viable cell.

関連する標識済み抗体及び組成の異なる製品 (6)

  • Carrier free

    Anti-Sialoadhesin/CD169 antibody [EPR27102-11] - BSA and Azide free

  • Unconjugated

    Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

  • 660 APC

    APC Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

  • 603 Alexa Fluor® 568

    Alexa Fluor® 568 Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Sialoadhesin/CD169 antibody [EPR27102-11]

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR27102-11

アイソタイプ

IgG

標識

PE

励起波長/蛍光波長

Ex: 480;565nm, Em: 578nm

キャリアフリー

No

交差種

Mouse, Mouse, Rat

アプリケーション

Flow Cyt, ICC/IF, IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/5000", "FlowCyt-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" }, "Rat": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
+4°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle|Store in the dark
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed : 24788876). Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs) (PubMed : 26370074). In turn, enhances macrophage-to-T-cell transmission of several viruses including murine leukemia virus (PubMed : 26370074). Acts as an endocytic receptor mediating clathrin dependent endocytosis. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. Plays a role in the inhibition of antiviral innate immune by promoting TBK1 degradation via TYROBP and TRIM27-mediated ubiquitination (By similarity).
See full target information Siglec1
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組合せ製品

Assay Kits

AB213757

Human CD169 ELISA Kit (SIGLEC-1)

Sandwich ELISA - Human CD169 ELISA Kit (SIGLEC-1) (AB213757)

  • 0
  • 0

Abcam product promise

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